# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA404431 | 1 | Activity | = | 60 | % | ALA5246865 | % | Plasmodium berghei | |||
2. | ALA404431 | 1 | Activity | = | 0.01 | % | ALA5246856 | % | Plasmodium falciparum | |||
3. | ALA404431 | 1 | IC50 | = | 0.91 | ng/ml | ALA5246790 | ug.mL-1 | Plasmodium falciparum | |||
4. | ALA404431 | 1 | IC50 | = | 1 | ng/ml | ALA5246789 | ug.mL-1 | Plasmodium falciparum | |||
5. | ALA404431 | 1 | Activity | = | 67 | % | ALA5246788 | % | Plasmodium berghei | |||
6. | ALA404431 | 1 | IC50 | = | 1.8 | nM | ALA4425206 | 8.74 | nM | Plasmodium falciparum | ||
7. | ALA404431 | 1 | Activity | = | 99 | % | ALA4425207 | % | Plasmodium berghei | |||
8. | ALA404431 | 1 | F | = | 13 | % | ALA4425208 | % | ||||
9. | ALA404431 | 1 | t1/2 | = | 128 | min | ALA4836667 | hr | ||||
10. | ALA404431 | 1 | CLH | = | 5.4 | microL/min/mg | ALA4836666 | mL.min-1.g-1 | ||||
11. | ALA404431 | 1 | EC50 | = | 2.5 | nM | ALA4836656 | 8.60 | nM | Plasmodium falciparum | ||
12. | ALA404431 | 1 | Time | = | 3 | hr | ALA4040246 | hr | Plasmodium falciparum | |||
13. | ALA404431 | 1 | Time | = | 1 | hr | ALA4040269 | hr | Plasmodium falciparum | |||
14. | ALA404431 | 1 | PD100 | = | 10 | mg/kg/day | ALA4040252 | mg/kg/day | Plasmodium berghei | |||
15. | ALA404431 | 1 | Stability | 0 | ALA4040268 | Stable | % | Mus musculus | ||||
16. | ALA404431 | 1 | Activity | = | 100 | % | ALA4040256 | % | Plasmodium berghei | |||
17. | ALA404431 | 1 | Activity | = | 80 | % | ALA4040255 | % | Plasmodium berghei | |||
18. | ALA404431 | 1 | Activity | = | 20 | % | ALA4040253 | % | Plasmodium berghei | |||
19. | ALA404431 | 1 | Activity | = | 0 | % | ALA4040254 | % | Plasmodium berghei | |||
20. | ALA404431 | 1 | PD50 | = | 4 | mg/kg/day | ALA4040252 | mg/kg/day | Plasmodium berghei |