| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA408444 | 8, brivanib alaninate, BMS-582664 | Stability | = | 100 | % | ALA935244 | % | Homo sapiens | |||
| 2. | ALA408444 | 8, brivanib alaninate, BMS-582664 | Stability | = | 100 | % | ALA935243 | % | Mus musculus | |||
| 3. | ALA408444 | 8, brivanib alaninate, BMS-582664 | TGI | = | 97 | % | ALA935259 | % | Homo sapiens | |||
| 4. | ALA408444 | 8, brivanib alaninate, BMS-582664 | TGI | = | 85 | % | ALA935258 | % | Homo sapiens | |||
| 5. | ALA408444 | 8, brivanib alaninate, BMS-582664 | Activity | 0 | ALA935257 | Dose-dependent effect | Homo sapiens | |||||
| 6. | ALA408444 | 8, brivanib alaninate, BMS-582664 | Solubility | = | 73 | mg/ml | ALA935255 | ug.mL-1 | ||||
| 7. | ALA408444 | 8, brivanib alaninate, BMS-582664 | Stability | = | 0.3 | % | ALA935254 | % | ||||
| 8. | ALA408444 | 8, brivanib alaninate, BMS-582664 | Stability | < | 1 | % | ALA935256 | % | ||||
| 9. | ALA408444 | 8, brivanib alaninate, BMS-582664 | IC50 | = | 1.6 | uM | ALA935240 | 5.80 | nM | Homo sapiens | ||
| 10. | ALA408444 | 8, brivanib alaninate, BMS-582664 | IC50 | = | 0.51 | uM | ALA935239 | 6.29 | nM | Homo sapiens | ||
| 11. | ALA408444 | 8, brivanib alaninate, BMS-582664 | IC50 | = | 24 | uM | ALA935253 | 4.62 | nM | Homo sapiens | ||
| 12. | ALA408444 | 8, brivanib alaninate, BMS-582664 | IC50 | = | 2.1 | uM | ALA935252 | 5.68 | nM | Homo sapiens | ||
| 13. | ALA408444 | 8, brivanib alaninate, BMS-582664 | IC50 | = | 9.7 | uM | ALA935251 | 5.01 | nM | Homo sapiens | ||
| 14. | ALA408444 | 8, brivanib alaninate, BMS-582664 | IC50 | > | 40 | uM | ALA935250 | nM | Homo sapiens | |||
| 15. | ALA408444 | 8, brivanib alaninate, BMS-582664 | Ratio | = | 4 | ALA935249 | Mus musculus | |||||
| 16. | ALA408444 | 8, brivanib alaninate, BMS-582664 | AUC | = | 276 | uM.hr | ALA935248 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | Mus musculus | ||
| 17. | ALA408444 | 8, brivanib alaninate, BMS-582664 | AUC | = | 69 | uM.hr | ALA935247 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | Mus musculus | ||
| 18. | ALA408444 | 8, brivanib alaninate, BMS-582664 | Cmax | = | 78 | uM | ALA935246 | nM | Mus musculus | |||
| 19. | ALA408444 | 8, brivanib alaninate, BMS-582664 | Cmax | = | 21 | uM | ALA935245 | nM | Mus musculus |
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