# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | 5α-Pregnane-3,20-dione | Allo-pregnandione | log(RBA) | = | 1.4 | ALA3281645 | ||||||
2. | 5α-Pregnane-3,20-dione | Allo-pregnandione | log(RBA) | = | 1.74 | ALA3281644 | Oryctolagus cuniculus | |||||
3. | 5α-Pregnane-3,20-dione | Allo-pregnandione | log(RBA) | = | 1.48 | ALA3281643 | Ovis aries | |||||
4. | 5α-Pregnane-3,20-dione | Allo-pregnandione | log(RBA) | = | 1.48 | ALA3281642 | Homo sapiens | |||||
5. | 5α-Pregnane-3,20-dione | Allo-pregnandione | Ratio | = | 1 | ALA3420915 | ||||||
6. | 5α-Pregnane-3,20-dione | Allo-pregnandione | inhibition | = | 0.48 | % | ALA4513082 | % | Severe acute respiratory syndrome coronavirus 2 | |||
7. | 5α-Pregnane-3,20-dione | Allo-pregnandione | Inhibition | = | 11.85 | % | ALA4495582 | % | Severe acute respiratory syndrome coronavirus 2 | |||
8. | 5α-Pregnane-3,20-dione | Allo-pregnandione | inhibition | = | 0.48 | % | ALA4513082 | % | Severe acute respiratory syndrome coronavirus 2 | |||
9. | 5α-Pregnane-3,20-dione | Allo-pregnandione | Efficacy | = | 72 | % | ALA949257 | % | Homo sapiens | |||
10. | 5α-Pregnane-3,20-dione | Allo-pregnandione | EC50 | = | 0.29 | uM | ALA949256 | 6.54 | nM | Homo sapiens | ||
11. | 5α-Pregnane-3,20-dione | Allo-pregnandione | LD50 | = | 0.84 | ug ml-1 | ALA691164 | ug ml-1 | Homo sapiens | |||
12. | 5α-Pregnane-3,20-dione | Allo-pregnandione | Remaining activity | = | 73 | % | ALA666775 | % | Mus musculus |