# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA488224 | 9k | pEC50 | = | 8.3 | ALA1002998 | 8.30 | nM | ||||
2. | ALA488224 | 9k | pEC50 | = | 8.9 | ALA1007108 | 8.90 | nM | Canis lupus familiaris | |||
3. | ALA488224 | 9k | pEC50 | = | 9.6 | ALA1007087 | 9.60 | nM | Homo sapiens | |||
4. | ALA488224 | 9k | EC50 | = | 14.1 | nM | ALA1002998 | 7.85 | nM | |||
5. | ALA488224 | 9k | PPB | = | 89 | % | ALA1002999 | % | Canis lupus familiaris | |||
6. | ALA488224 | 9k | EC50 | = | 4 | nM | ALA1007111 | 8.40 | nM | Canis lupus familiaris | ||
7. | ALA488224 | 9k | ED50 | = | 65 | ug/kg | ALA1007111 | mg.kg-1 | Canis lupus familiaris | |||
8. | ALA488224 | 9k | INH | 0 | ALA1007109 | Not Determined | % | Canis lupus familiaris | ||||
9. | ALA488224 | 9k | EC50 | = | 1.3 | nM | ALA1007108 | 8.89 | nM | Canis lupus familiaris | ||
10. | ALA488224 | 9k | EC50 | = | 0.26 | nM | ALA1007087 | 9.59 | nM | Homo sapiens | ||
11. | ALA488224 | 9k | EC50 | > | 1000 | nM | ALA1007086 | nM | Homo sapiens | |||
12. | ALA488224 | 9k | EC50 | = | 480 | nM | ALA1007085 | 6.32 | nM | Homo sapiens | ||
13. | ALA488224 | 9k | Ratio | = | 0.48 | ALA1007088 | Canis lupus familiaris | |||||
14. | ALA488224 | 9k | F | = | 10.7 | % | ALA947280 | % | Macaca mulatta | |||
15. | ALA488224 | 9k | F | = | 60 | % | ALA947267 | % | Canis lupus familiaris | |||
16. | ALA488224 | 9k | F | = | 82.5 | % | ALA947279 | % | Rattus norvegicus | |||
17. | ALA488224 | 9k | CL | = | 3.4 | ml/min.kg | ALA947284 | mL.min-1.kg-1 | Macaca mulatta | |||
18. | ALA488224 | 9k | CL | = | 47.7 | ml/min.kg | ALA947273 | mL.min-1.kg-1 | Canis lupus familiaris | |||
19. | ALA488224 | 9k | CL | = | 15.8 | ml/min.kg | ALA947283 | mL.min-1.kg-1 | Rattus norvegicus | |||
20. | ALA488224 | 9k | beta t1/2 | = | 10.3 | hr | ALA947282 | hr | Macaca mulatta |