Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	Dexmedetomidine	2	LogD7.4		2.79		ALA3301363
2.	Dexmedetomidine	2	inhibition	=	1.23	%	ALA4808150			%	Homo sapiens
3.	Dexmedetomidine	2	inhibition	=	-13.41	%	ALA4808149			%	Homo sapiens
4.	Dexmedetomidine	2	DILI_Concern		0		ALA4029350		Ambiguous-Dili-Concern		Homo sapiens
5.	Dexmedetomidine	2	DILI_severity_class	=	4		ALA4029349				Homo sapiens
6.	Dexmedetomidine	2	Activity	=	50	%	ALA3882414			%	Mus musculus
7.	Dexmedetomidine	2	Activity	=	100	%	ALA3882413			%	Mus musculus
8.	Dexmedetomidine	2	Ratio EC50	=	289		ALA3882410
9.	Dexmedetomidine	2	Emax	=	62	%	ALA3882409			%	Cricetulus griseus
10.	Dexmedetomidine	2	EC50	=	364	nM	ALA3882408	6.44		nM	Cricetulus griseus
11.	Dexmedetomidine	2	Emax	=	59	%	ALA3882407			%	Bos taurus
12.	Dexmedetomidine	2	EC50	=	376	nM	ALA3882406	6.42		nM	Bos taurus
13.	Dexmedetomidine	2	Emax	=	90	%	ALA3882405			%	Homo sapiens
14.	Dexmedetomidine	2	EC50	=	0.48	nM	ALA3882404	9.32		nM	Homo sapiens
15.	Dexmedetomidine	2	Emax	=	93	%	ALA3882403			%	Homo sapiens
16.	Dexmedetomidine	2	EC50	=	0.8	nM	ALA3882402	9.10		nM	Homo sapiens
17.	Dexmedetomidine	2	Intrinsic activity	=	63	%	ALA3815855			%	Homo sapiens
18.	Dexmedetomidine	2	pEC50	=	8.67		ALA3815854	8.67		nM	Homo sapiens
19.	Dexmedetomidine	2	Ki(app)	=	2.5	nM	ALA3815853	8.60		nM	Homo sapiens
20.	Dexmedetomidine	2	INH		0		ALA5137734		NA	%	Homo sapiens