# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA511115 | 1 (Ariflo) | ED50 | = | 17 | uM/g | ALA5236729 | umol.kg-1 | Rattus norvegicus | |||
2. | ALA511115 | 1 (Ariflo) | ED50 | > | 30 | uM/g | ALA5236728 | umol.kg-1 | Mus musculus | |||
3. | ALA511115 | 1 (Ariflo) | EC50 | = | 3.47 | nM | ALA5236727 | 8.46 | nM | |||
4. | ALA511115 | 1 (Ariflo) | IC50 | = | 813 | nM | ALA5236726 | 6.09 | nM | Homo sapiens | ||
5. | ALA511115 | 1 (Ariflo) | IC50 | = | 288 | nM | ALA5236725 | 6.54 | nM | Homo sapiens | ||
6. | ALA511115 | 1 (Ariflo) | IC50 | = | 398 | nM | ALA5236724 | 6.40 | nM | Homo sapiens | ||
7. | ALA511115 | 1 (Ariflo) | IC50 | = | 63 | nM | ALA5236673 | 7.20 | nM | Homo sapiens | ||
8. | ALA511115 | 1 (Ariflo) | IC50 | = | 95 | nM | ALA5152104 | 7.02 | nM | Homo sapiens | ||
9. | ALA511115 | 1 (Ariflo) | Ratio IC50 | = | 182 | ALA3362054 | ||||||
10. | ALA511115 | 1 (Ariflo) | IC50 | = | 16 | uM | ALA3361696 | 4.80 | nM | Trypanosoma brucei | ||
11. | ALA511115 | 1 (Ariflo) | EC50 | > | 50 | uM | ALA3362056 | nM | Trypanosoma brucei | |||
12. | ALA511115 | 1 (Ariflo) | TC50 | > | 50 | uM | ALA3362055 | uM | ||||
13. | ALA511115 | 1 (Ariflo) | LogD7.4 | 0.76 | ALA3301363 | |||||||
14. | ALA511115 | 1 (Ariflo) | PPB | 98.84 | % | ALA3301365 | % | |||||
15. | ALA511115 | 1 (Ariflo) | PPB | 93.94 | % | ALA3301366 | % | |||||
16. | ALA511115 | 1 (Ariflo) | CLint | 28 | microL/min/1E6 cells | ALA3301371 | uL.min-1.(10^6cells)-1 | |||||
17. | ALA511115 | 1 (Ariflo) | CLint | 13 | microL/min/mg | ALA3301370 | mL.min-1.g-1 | |||||
18. | ALA511115 | 1 (Ariflo) | IC50 | = | 70 | nM | ALA3871030 | 7.16 | nM | |||
19. | ALA511115 | 1 (Ariflo) | IC50 | = | 25 | nM | ALA4425316 | 7.60 | nM | Homo sapiens | ||
20. | ALA511115 | 1 (Ariflo) | IC50 | = | 11 | nM | ALA4425320 | 7.96 | nM | Homo sapiens |