| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA446806 | 9e | pEC50 | = | 8.4 | ALA1002998 | 8.40 | nM | ||||
| 2. | ALA446806 | 9e | pEC50 | = | 8.9 | ALA1007108 | 8.90 | nM | Canis lupus familiaris | |||
| 3. | ALA446806 | 9e | pEC50 | = | 10.5 | ALA1007087 | 10.50 | nM | Homo sapiens | |||
| 4. | ALA446806 | 9e | EC50 | = | 4.4 | nM | ALA1002998 | 8.36 | nM | |||
| 5. | ALA446806 | 9e | PPB | = | 76 | % | ALA1002999 | % | Canis lupus familiaris | |||
| 6. | ALA446806 | 9e | EC50 | = | 1.2 | nM | ALA1007111 | 8.92 | nM | Canis lupus familiaris | ||
| 7. | ALA446806 | 9e | ED50 | = | 14.3 | ug/kg | ALA1007111 | mg.kg-1 | Canis lupus familiaris | |||
| 8. | ALA446806 | 9e | INH | > | 70 | % | ALA1007109 | % | Canis lupus familiaris | |||
| 9. | ALA446806 | 9e | EC50 | = | 1.2 | nM | ALA1007108 | 8.92 | nM | Canis lupus familiaris | ||
| 10. | ALA446806 | 9e | F | = | 0 | % | ALA1007107 | % | Macaca mulatta | |||
| 11. | ALA446806 | 9e | CL | = | 52 | ml/min.kg | ALA1007106 | mL.min-1.kg-1 | Macaca mulatta | |||
| 12. | ALA446806 | 9e | beta t1/2 | 0 | ALA1007105 | Not Determined | Macaca mulatta | |||||
| 13. | ALA446806 | 9e | EC50 | = | 140 | nM | ALA1007085 | 6.85 | nM | Homo sapiens | ||
| 14. | ALA446806 | 9e | EC50 | = | 290 | nM | ALA1007086 | 6.54 | nM | Homo sapiens | ||
| 15. | ALA446806 | 9e | EC50 | = | 0.029 | nM | ALA1007087 | 10.54 | nM | Homo sapiens | ||
| 16. | ALA446806 | 9e | Cmax | = | 2.5 | ng/ml | ALA1007089 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Canis lupus familiaris | ||
| 17. | ALA446806 | 9e | AUC | = | 26.7 | ng.hr/ml | ALA1007090 | ng.hr.mL-1 | Canis lupus familiaris | |||
| 18. | ALA446806 | 9e | beta t1/2 | = | 6.7 | hr | ALA1007091 | hr | Canis lupus familiaris | |||
| 19. | ALA446806 | 9e | CL | = | 34.9 | ml/min.kg | ALA1007092 | mL.min-1.kg-1 | Canis lupus familiaris | |||
| 20. | ALA446806 | 9e | F | = | 54 | % | ALA1007093 | % | Canis lupus familiaris |
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