# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA33700 | 72 (table 5) | Activity | 0 | ALA3231300 | Active | Rattus norvegicus | |||||
2. | ALA33700 | 72 (table 5) | Activity | 0 | ALA4057011 | Not Active | Oryctolagus cuniculus | |||||
3. | ALA33700 | 72 (table 5) | LD50 | > | 2400 | mg kg-1 | ALA4057006 | mg.kg-1 | Rattus norvegicus | |||
4. | ALA33700 | 72 (table 5) | Time | = | 2 | hr | ALA4057005 | hr | Oryctolagus cuniculus | |||
5. | ALA33700 | 72 (table 5) | Activity | = | 8 | % | ALA4057004 | % | Oryctolagus cuniculus | |||
6. | ALA33700 | 72 (table 5) | IC50 | = | 5.7 | uM | ALA4056998 | 5.24 | nM | Homo sapiens | ||
7. | ALA33700 | 72 (table 5) | Imax | = | 101.9 | % | ALA4057001 | % | Homo sapiens | |||
8. | ALA33700 | 72 (table 5) | pIC50 | = | 8.55 | ALA1016924 | 8.55 | nM | Homo sapiens | |||
9. | ALA33700 | 72 (table 5) | Selectivity | = | 1.1 | ALA881807 | ||||||
10. | ALA33700 | 72 (table 5) | Selectivity | = | 0.929 | ALA841235 | ||||||
11. | ALA33700 | 72 (table 5) | Ki | = | 3.1 | nM | ALA710823 | 8.51 | nM | Homo sapiens | ||
12. | ALA33700 | 72 (table 5) | Ki | = | 2.6 | nM | ALA713259 | 8.59 | nM | Homo sapiens | ||
13. | ALA33700 | 72 (table 5) | Ki | = | 2.8 | nM | ALA713109 | 8.55 | nM | Homo sapiens | ||
14. | ALA33700 | 72 (table 5) | Relative affinity | = | -0.77 | ALA713142 | Homo sapiens | |||||
15. | ALA33700 | 72 (table 5) | Relative affinity | = | -1.13 | ALA715950 | Homo sapiens | |||||
16. | ALA33700 | 72 (table 5) | Intrinsic activity | = | 0.98 | ALA710593 | Homo sapiens | |||||
17. | ALA33700 | 72 (table 5) | Log Ki | = | -8.76 | ALA858415 | 8.76 | nM | Homo sapiens | |||
18. | ALA33700 | 72 (table 5) | Intrinsic activity | = | 1.06 | ALA714100 | Homo sapiens | |||||
19. | ALA33700 | 72 (table 5) | Log Ki | = | -8.65 | ALA715954 | 8.65 | nM | Homo sapiens | |||
20. | ALA33700 | 72 (table 5) | Ki | = | 254 | nM | ALA712439 | 6.59 | nM | Gallus gallus |