Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Comment	Assay	Assay Organism
1.	ALA481931	30, MK-0731	pKa	=	7.6		ALA2208725
2.	ALA481931	30, MK-0731	Ratio	=	4.5		ALA1694351			Homo sapiens
3.	ALA481931	30, MK-0731	FC	>	500		ALA1694350
4.	ALA481931	30, MK-0731	EC90	=	94	nM	ALA1020036		nM	Homo sapiens
5.	ALA481931	30, MK-0731	Activity		0		ALA1015708	Not Active
6.	ALA481931	30, MK-0731	Activity		0		ALA1020074	Not Active
7.	ALA481931	30, MK-0731	MTD	=	100	mg kg-1	ALA1015710		mg kg-1	Mus musculus
8.	ALA481931	30, MK-0731	MTD	=	12	mg kg-1	ALA1015709		mg kg-1	Mus musculus
9.	ALA481931	30, MK-0731	t1/2	=	1	hr	ALA1020070		hr	Macaca mulatta
10.	ALA481931	30, MK-0731	t1/2	=	2	hr	ALA1020067		hr	Canis lupus familiaris
11.	ALA481931	30, MK-0731	Vdss	=	2.3	L/Kg	ALA1020069		L.kg-1	Macaca mulatta
12.	ALA481931	30, MK-0731	Vdss	=	1.6	L/Kg	ALA1020066		L.kg-1	Canis lupus familiaris
13.	ALA481931	30, MK-0731	CL	=	23.1	ml/min.kg	ALA1020068		mL.min-1.kg-1	Macaca mulatta
14.	ALA481931	30, MK-0731	CL	=	15.1	ml/min.kg	ALA1020065		mL.min-1.kg-1	Canis lupus familiaris
15.	ALA481931	30, MK-0731	t1/2	=	1	hr	ALA1020064		hr	Rattus norvegicus
16.	ALA481931	30, MK-0731	Vdss	=	3	L/Kg	ALA1020063		L.kg-1	Rattus norvegicus
17.	ALA481931	30, MK-0731	CL	=	66.7	ml/min.kg	ALA1020062		mL.min-1.kg-1	Rattus norvegicus
18.	ALA481931	30, MK-0731	Activity		0		ALA1020061	Non-toxic		Rattus norvegicus
19.	ALA481931	30, MK-0731	solubility	>	50	mg/ml	ALA1020060		ug.mL-1
20.	ALA481931	30, MK-0731	Activity	=	90	%	ALA1020059		%