# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA493671 | 16 | F | = | 72 | % | ALA1025682 | % | Rattus norvegicus | |||
2. | ALA493671 | 16 | AUC | = | 21097 | ng.hr/ml | ALA1025681 | ng.hr.mL-1 | Rattus norvegicus | |||
3. | ALA493671 | 16 | t1/2 | = | 9.9 | hr | ALA1025680 | hr | Rattus norvegicus | |||
4. | ALA493671 | 16 | Vdss | = | 4.7 | L/Kg | ALA1025679 | L.kg-1 | Rattus norvegicus | |||
5. | ALA493671 | 16 | CL | = | 0.35 | L/hr/kg | ALA1025678 | mL.min-1.kg-1 | Rattus norvegicus | |||
6. | ALA493671 | 16 | IC50 | = | 2.7 | nM | ALA1025675 | 8.57 | nM | Homo sapiens | ||
7. | ALA493671 | 16 | IC50 | = | 0.4 | nM | ALA1025674 | 9.40 | nM | Homo sapiens | ||
8. | ALA493671 | 16 | IC50 | > | 10000 | nM | ALA1025671 | nM | Homo sapiens | |||
9. | ALA493671 | 16 | IC50 | = | 7772 | nM | ALA1025670 | 5.11 | nM | Homo sapiens | ||
10. | ALA493671 | 16 | IC50 | > | 10000 | nM | ALA1025669 | nM | Homo sapiens | |||
11. | ALA493671 | 16 | IC50 | = | 1061 | nM | ALA1024856 | 5.97 | nM | Homo sapiens | ||
12. | ALA493671 | 16 | IC50 | > | 5000 | nM | ALA1024855 | nM | Homo sapiens | |||
13. | ALA493671 | 16 | IC50 | = | 2680 | nM | ALA1024854 | 5.57 | nM | Homo sapiens | ||
14. | ALA493671 | 16 | IC50 | = | 1 | nM | ALA1024853 | 9.00 | nM | Homo sapiens | ||
15. | ALA493671 | 16 | AUC | = | 123 | nM.hr | ALA986284 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | Rattus norvegicus | ||
16. | ALA493671 | 16 | ED50 | = | 0.04 | mg kg-1 | ALA986283 | mg.kg-1 | Rattus norvegicus | |||
17. | ALA493671 | 16 | ED50 | < | 0.03 | mg kg-1 | ALA1025683 | mg.kg-1 | Rattus norvegicus | |||
18. | ALA493671 | 16 | IC50 | = | 88 | nM | ALA1025672 | 7.06 | nM | |||
19. | ALA493671 | 16 | IC50 | = | 954 | nM | ALA986285 | 6.02 | nM | Homo sapiens |