# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA495113 | (R,R)-30 | Vdss | = | 1.2 | L/Kg | ALA1024682 | L.kg-1 | Canis lupus familiaris | |||
2. | ALA495113 | (R,R)-30 | Vdss | = | 3.2 | L/Kg | ALA1024678 | L.kg-1 | Rattus norvegicus | |||
3. | ALA495113 | (R,R)-30 | t1/2 | = | 7.8 | hr | ALA1024681 | hr | Canis lupus familiaris | |||
4. | ALA495113 | (R,R)-30 | t1/2 | = | 4.4 | hr | ALA1024677 | hr | Rattus norvegicus | |||
5. | ALA495113 | (R,R)-30 | CL | = | 1.8 | ml/min.kg | ALA1024680 | mL.min-1.kg-1 | Canis lupus familiaris | |||
6. | ALA495113 | (R,R)-30 | CL | = | 14 | ml/min.kg | ALA1024676 | mL.min-1.kg-1 | Rattus norvegicus | |||
7. | ALA495113 | (R,R)-30 | F | = | 31 | % | ALA1024679 | % | Canis lupus familiaris | |||
8. | ALA495113 | (R,R)-30 | F | = | 25 | % | ALA1024675 | % | Rattus norvegicus | |||
9. | ALA495113 | (R,R)-30 | Selectivity ratio | = | 110 | ALA1023838 | ||||||
10. | ALA495113 | (R,R)-30 | Selectivity ratio | = | 1100 | ALA1023837 | ||||||
11. | ALA495113 | (R,R)-30 | Selectivity ratio | = | 1700 | ALA1023836 | ||||||
12. | ALA495113 | (R,R)-30 | Selectivity ratio | > | 140000 | ALA1023835 | ||||||
13. | ALA495113 | (R,R)-30 | Selectivity ratio | = | 6000 | ALA1023834 | ||||||
14. | ALA495113 | (R,R)-30 | Ratio IC50 | = | 6 | ALA1023833 | ||||||
15. | ALA495113 | (R,R)-30 | IC50 | = | 51 | nM | ALA1023832 | 7.29 | nM | |||
16. | ALA495113 | (R,R)-30 | Selectivity ratio | = | 7100 | ALA1023826 | ||||||
17. | ALA495113 | (R,R)-30 | Selectivity ratio | > | 14000 | ALA1023825 | ||||||
18. | ALA495113 | (R,R)-30 | Selectivity ratio | = | 9500 | ALA1023824 | ||||||
19. | ALA495113 | (R,R)-30 | IC50 | = | 9.3 | nM | ALA1023823 | 8.03 | nM | Oryctolagus cuniculus | ||
20. | ALA495113 | (R,R)-30 | IC50 | = | 0.69 | nM | ALA1023822 | 9.16 | nM |