Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Assay	Assay Organism
1.	ALA523352	(R,R)-31	Ratio IC50	=	714		ALA5106300			Homo sapiens
2.	ALA523352	(R,R)-31	Ratio IC50	=	40		ALA5106299
3.	ALA523352	(R,R)-31	Ratio IC50	=	1355		ALA5106298			Homo sapiens
4.	ALA523352	(R,R)-31	Ratio IC50	=	5556		ALA5106297			Homo sapiens
5.	ALA523352	(R,R)-31	Ratio IC50	=	1711		ALA5106296			Homo sapiens
6.	ALA523352	(R,R)-31	IC50	=	1.8	nM	ALA5106294	8.74	nM	Homo sapiens
7.	ALA523352	(R,R)-31	Selectivity ratio	=	4300		ALA1119725
8.	ALA523352	(R,R)-31	Selectivity ratio	=	4700		ALA1119724
9.	ALA523352	(R,R)-31	Selectivity ratio	>	16000		ALA1119723
10.	ALA523352	(R,R)-31	Selectivity ratio	=	110		ALA1120137
11.	ALA523352	(R,R)-31	Selectivity ratio	>	140000		ALA1120136
12.	ALA523352	(R,R)-31	Selectivity ratio	=	1100		ALA1120135
13.	ALA523352	(R,R)-31	IC50	=	0.62	nM	ALA1119721	9.21	nM	Homo sapiens
14.	ALA523352	(R,R)-31	Vdss	=	3.4	L/Kg	ALA1024686		L.kg-1	Macaca mulatta
15.	ALA523352	(R,R)-31	Vdss	=	2.1	L/Kg	ALA1024682		L.kg-1	Canis lupus familiaris
16.	ALA523352	(R,R)-31	Vdss	=	2.8	L/Kg	ALA1024678		L.kg-1	Rattus norvegicus
17.	ALA523352	(R,R)-31	t1/2	=	13	hr	ALA1024685		hr	Macaca mulatta
18.	ALA523352	(R,R)-31	t1/2	=	34	hr	ALA1024681		hr	Canis lupus familiaris
19.	ALA523352	(R,R)-31	t1/2	=	4.4	hr	ALA1024677		hr	Rattus norvegicus
20.	ALA523352	(R,R)-31	CL	=	5	ml/min.kg	ALA1024684		mL.min-1.kg-1	Macaca mulatta