| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA460990 | 16, CEP-6331 | Stability | = | 44 | % | ALA996140 | % | ||||
| 2. | ALA460990 | 16, CEP-6331 | IC50 | = | 1855 | nM | ALA1000437 | 5.73 | nM | Homo sapiens | ||
| 3. | ALA460990 | 16, CEP-6331 | Activity | 0 | ALA996145 | Active | Mus musculus | |||||
| 4. | ALA460990 | 16, CEP-6331 | Cp | = | 0.58 | uM | ALA996143 | uM | Mus musculus | |||
| 5. | ALA460990 | 16, CEP-6331 | Activity | = | 64 | % | ALA996142 | % | Mus musculus | |||
| 6. | ALA460990 | 16, CEP-6331 | IC50 | = | 43 | nM | ALA996141 | 7.37 | nM | Homo sapiens | ||
| 7. | ALA460990 | 16, CEP-6331 | F | = | 37 | % | ALA996139 | % | Rattus norvegicus | |||
| 8. | ALA460990 | 16, CEP-6331 | t1/2 | = | 1.1 | hr | ALA996137 | hr | Rattus norvegicus | |||
| 9. | ALA460990 | 16, CEP-6331 | Cmax | = | 339 | ng/ml | ALA996135 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
| 10. | ALA460990 | 16, CEP-6331 | AUC | = | 1073 | ng.hr/ml | ALA996133 | ng.hr.mL-1 | Rattus norvegicus | |||
| 11. | ALA460990 | 16, CEP-6331 | CL | = | 28 | ml/min.kg | ALA996131 | mL.min-1.kg-1 | Rattus norvegicus | |||
| 12. | ALA460990 | 16, CEP-6331 | Vd | = | 2 | L/Kg | ALA996129 | L.kg-1 | Rattus norvegicus | |||
| 13. | ALA460990 | 16, CEP-6331 | AUC | = | 579 | ng.hr/ml | ALA996127 | ng.hr.mL-1 | Rattus norvegicus | |||
| 14. | ALA460990 | 16, CEP-6331 | t1/2 | = | 0.8 | hr | ALA996125 | hr | Rattus norvegicus | |||
| 15. | ALA460990 | 16, CEP-6331 | Ratio IC50 | = | 100 | ALA996123 | ||||||
| 16. | ALA460990 | 16, CEP-6331 | Ratio IC50 | > | 30 | ALA996122 | ||||||
| 17. | ALA460990 | 16, CEP-6331 | IC50 | = | 1190 | nM | ALA996121 | 5.92 | nM | Homo sapiens | ||
| 18. | ALA460990 | 16, CEP-6331 | IC50 | > | 10000 | nM | ALA996120 | nM | Homo sapiens | |||
| 19. | ALA460990 | 16, CEP-6331 | IC50 | > | 10000 | nM | ALA996119 | nM | Homo sapiens | |||
| 20. | ALA460990 | 16, CEP-6331 | IC50 | > | 10000 | nM | ALA996118 | nM | Homo sapiens |
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