# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA461619 | 7g | t1/2 | = | 0.7 | hr | ALA967047 | hr | Rattus norvegicus | |||
2. | ALA461619 | 7g | Activity | = | 40 | % | ALA969766 | % | Rattus norvegicus | |||
3. | ALA461619 | 7g | Activity | 0 | ALA969772 | Non-toxic | ||||||
4. | ALA461619 | 7g | Activity | 0 | ALA969771 | Not Active | Homo sapiens | |||||
5. | ALA461619 | 7g | Activity | 0 | ALA969770 | Not Active | Homo sapiens | |||||
6. | ALA461619 | 7g | Activity | 0 | ALA969769 | Not Active | Homo sapiens | |||||
7. | ALA461619 | 7g | Activity | 0 | ALA969768 | Not Active | Homo sapiens | |||||
8. | ALA461619 | 7g | Activity | 0 | ALA969767 | Not Active | Homo sapiens | |||||
9. | ALA461619 | 7g | Activity | 0 | ALA969765 | Not Active | Rattus norvegicus | |||||
10. | ALA461619 | 7g | Activity | 0 | ALA967060 | Dose-dependent effect | Rattus norvegicus | |||||
11. | ALA461619 | 7g | IC50 | = | 20 | nM | ALA967056 | 7.70 | nM | Mus musculus | ||
12. | ALA461619 | 7g | IC50 | > | 10000 | nM | ALA967055 | nM | Rattus norvegicus | |||
13. | ALA461619 | 7g | IC50 | > | 10000 | nM | ALA967054 | nM | Rattus norvegicus | |||
14. | ALA461619 | 7g | IC50 | > | 10000 | nM | ALA967053 | nM | ||||
15. | ALA461619 | 7g | IC50 | = | 28 | nM | ALA967052 | 7.55 | nM | |||
16. | ALA461619 | 7g | Vd | = | 3.7 | L/Kg | ALA967051 | L.kg-1 | Rattus norvegicus | |||
17. | ALA461619 | 7g | Cmax | = | 37 | nM | ALA967050 | nM | Rattus norvegicus | |||
18. | ALA461619 | 7g | AUC | = | 131 | nM.hr | ALA967049 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | Rattus norvegicus | ||
19. | ALA461619 | 7g | F | = | 21 | % | ALA967048 | % | Rattus norvegicus | |||
20. | ALA461619 | 7g | CL | = | 3.1 | L/hr/kg | ALA967046 | mL.min-1.kg-1 | Rattus norvegicus |