# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA523034 | (S)-14, MMP408 | Ratio IC50 | = | 60 | ALA1937508 | ||||||
2. | ALA523034 | (S)-14, MMP408 | F | = | 27 | % | ALA958326 | % | Mus musculus | |||
3. | ALA523034 | (S)-14, MMP408 | AUC | = | 7476 | hr.ng/ml | ALA958325 | ng.hr.mL-1 | Mus musculus | |||
4. | ALA523034 | (S)-14, MMP408 | Cmax | = | 3084 | ng/ml | ALA958324 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Mus musculus | ||
5. | ALA523034 | (S)-14, MMP408 | t1/2 | = | 3 | hr | ALA960896 | hr | Mus musculus | |||
6. | ALA523034 | (S)-14, MMP408 | MED | = | 5 | mg kg-1 | ALA958342 | mg kg-1 | Mus musculus | |||
7. | ALA523034 | (S)-14, MMP408 | INH | > | 70 | % | ALA958341 | % | Mus musculus | |||
8. | ALA523034 | (S)-14, MMP408 | Activity | 0 | ALA958338 | Not Active | Homo sapiens | |||||
9. | ALA523034 | (S)-14, MMP408 | t1/2 | > | 60 | min | ALA958339 | hr | Homo sapiens | |||
10. | ALA523034 | (S)-14, MMP408 | t1/2 | > | 60 | min | ALA958337 | hr | ||||
11. | ALA523034 | (S)-14, MMP408 | t1/2 | > | 60 | min | ALA958336 | hr | ||||
12. | ALA523034 | (S)-14, MMP408 | t1/2 | > | 60 | min | ALA958335 | hr | Rattus norvegicus | |||
13. | ALA523034 | (S)-14, MMP408 | t1/2 | > | 60 | min | ALA958334 | hr | ||||
14. | ALA523034 | (S)-14, MMP408 | IC50 | = | 1100 | nM | ALA958333 | 5.96 | nM | Homo sapiens | ||
15. | ALA523034 | (S)-14, MMP408 | IC50 | > | 10 | nM | ALA958332 | nM | Homo sapiens | |||
16. | ALA523034 | (S)-14, MMP408 | IC50 | > | 5 | nM | ALA958331 | nM | Homo sapiens | |||
17. | ALA523034 | (S)-14, MMP408 | IC50 | > | 25 | nM | ALA958330 | nM | Homo sapiens | |||
18. | ALA523034 | (S)-14, MMP408 | IC50 | = | 1300 | nM | ALA958329 | 5.89 | nM | Homo sapiens | ||
19. | ALA523034 | (S)-14, MMP408 | IC50 | > | 22 | nM | ALA958328 | nM | Homo sapiens | |||
20. | ALA523034 | (S)-14, MMP408 | IC50 | = | 351 | nM | ALA958327 | 6.46 | nM | Homo sapiens |