| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA523034 | (S)-14, MMP408 | Ratio IC50 | = | 60 | ALA1937508 | ||||||
| 2. | ALA523034 | (S)-14, MMP408 | t1/2 | > | 30 | min | ALA1058831 | hr | Homo sapiens | |||
| 3. | ALA523034 | (S)-14, MMP408 | t1/2 | > | 30 | min | ALA1058830 | hr | Rattus norvegicus | |||
| 4. | ALA523034 | (S)-14, MMP408 | t1/2 | > | 30 | min | ALA1058829 | hr | ||||
| 5. | ALA523034 | (S)-14, MMP408 | Cmax | = | 3084 | ng/ml | ALA1062308 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Mus musculus | ||
| 6. | ALA523034 | (S)-14, MMP408 | t1/2 | = | 3 | hr | ALA1062306 | hr | Mus musculus | |||
| 7. | ALA523034 | (S)-14, MMP408 | CL | = | 17.2 | ml/min.kg | ALA1062305 | mL.min-1.kg-1 | Mus musculus | |||
| 8. | ALA523034 | (S)-14, MMP408 | Vdss | = | 1.9 | L/Kg | ALA1062304 | L.kg-1 | Mus musculus | |||
| 9. | ALA523034 | (S)-14, MMP408 | IC50 | = | 60 | nM | ALA1062300 | 7.22 | nM | Homo sapiens | ||
| 10. | ALA523034 | (S)-14, MMP408 | IC50 | = | 120 | nM | ALA1062302 | 6.92 | nM | Homo sapiens | ||
| 11. | ALA523034 | (S)-14, MMP408 | IC50 | = | 2 | nM | ALA1062301 | 8.70 | nM | Homo sapiens | ||
| 12. | ALA523034 | (S)-14, MMP408 | AUC | = | 249.2 | ng.hr/ml/mg/kg | ALA1062310 | ng.hr/ml/mg/kg | Mus musculus | |||
| 13. | ALA523034 | (S)-14, MMP408 | F | = | 27 | % | ALA1062312 | % | Mus musculus | |||
| 14. | ALA523034 | (S)-14, MMP408 | F | = | 27 | % | ALA958326 | % | Mus musculus | |||
| 15. | ALA523034 | (S)-14, MMP408 | AUC | = | 7476 | hr.ng/ml | ALA958325 | ng.hr.mL-1 | Mus musculus | |||
| 16. | ALA523034 | (S)-14, MMP408 | Cmax | = | 3084 | ng/ml | ALA958324 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Mus musculus | ||
| 17. | ALA523034 | (S)-14, MMP408 | t1/2 | = | 3 | hr | ALA960896 | hr | Mus musculus | |||
| 18. | ALA523034 | (S)-14, MMP408 | MED | = | 5 | mg kg-1 | ALA958342 | mg kg-1 | Mus musculus | |||
| 19. | ALA523034 | (S)-14, MMP408 | INH | > | 70 | % | ALA958341 | % | Mus musculus | |||
| 20. | ALA523034 | (S)-14, MMP408 | Activity | 0 | ALA958338 | Not Active | Homo sapiens |
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