| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA492529 | 21, DSM74 | IC50 | = | 0.28 | uM | ALA3878218 | 6.55 | nM | |||
| 2. | ALA492529 | 21, DSM74 | IC50 | = | 0.28 | uM | ALA4403493 | 6.55 | nM | |||
| 3. | ALA492529 | 21, DSM74 | PPB | = | 86.9 | % | ALA1785550 | % | Homo sapiens | |||
| 4. | ALA492529 | 21, DSM74 | solubility | = | 21 | uM | ALA1785549 | nM | ||||
| 5. | ALA492529 | 21, DSM74 | logD | = | 2.5 | ALA1785548 | ||||||
| 6. | ALA492529 | 21, DSM74 | CL | = | 8 | uL/min/mg | ALA1785551 | mL.min-1.g-1 | Homo sapiens | |||
| 7. | ALA492529 | 21, DSM74 | Kd | 0 | ALA3296351 | Not Determined | Rattus norvegicus | |||||
| 8. | ALA492529 | 21, DSM74 | IC50 | > | 100 | uM | ALA3296349 | nM | ||||
| 9. | ALA492529 | 21, DSM74 | IC50 | > | 100 | uM | ALA3296344 | nM | Mus musculus | |||
| 10. | ALA492529 | 21, DSM74 | IC50 | > | 100 | uM | ALA3296348 | nM | Rattus norvegicus | |||
| 11. | ALA492529 | 21, DSM74 | IC50 | > | 100 | uM | ALA3296347 | nM | Homo sapiens | |||
| 12. | ALA492529 | 21, DSM74 | logD | = | 3.55 | ALA3296352 | ||||||
| 13. | ALA492529 | 21, DSM74 | IC50 | = | 0.27 | uM | ALA3296346 | 6.57 | nM | Plasmodium falciparum | ||
| 14. | ALA492529 | 21, DSM74 | IC50 | = | 0.26 | uM | ALA3296345 | 6.58 | nM | Plasmodium falciparum | ||
| 15. | ALA492529 | 21, DSM74 | Kd | = | 0.17 | uM | ALA3296350 | 6.77 | nM | Plasmodium falciparum | ||
| 16. | ALA492529 | 21, DSM74 | Activity | 0 | ALA1016156 | Non-toxic | Mus musculus | |||||
| 17. | ALA492529 | 21, DSM74 | Activity | 0 | ALA1016151 | Non-toxic | Mus musculus | |||||
| 18. | ALA492529 | 21, DSM74 | Activity | = | 71 | % | ALA1016153 | % | Plasmodium berghei | |||
| 19. | ALA492529 | 21, DSM74 | Activity | = | 95 | % | ALA1016152 | % | Plasmodium berghei | |||
| 20. | ALA492529 | 21, DSM74 | AUC | = | 11757 | uM.min | ALA1016150 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | Mus musculus |
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