Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	6-chloro-1,2-benzoxazol-3-ol	CBIO	Stability	=	33	%	ALA3384565			%
2.	6-chloro-1,2-benzoxazol-3-ol	CBIO	Stability	=	58	%	ALA3384562			%
3.	6-chloro-1,2-benzoxazol-3-ol	CBIO	IC50	=	0.21	uM	ALA3807134	6.68		nM	Sus scrofa
4.	6-chloro-1,2-benzoxazol-3-ol	CBIO	IC50	=	90	nM	ALA3807135	7.05		nM	Rattus norvegicus
5.	6-chloro-1,2-benzoxazol-3-ol	CBIO	IC50	=	110	nM	ALA3807136	6.96		nM	Homo sapiens
6.	6-chloro-1,2-benzoxazol-3-ol	CBIO	Kd	=	0.87	uM	ALA4221098	6.06		nM	Sus scrofa
7.	6-chloro-1,2-benzoxazol-3-ol	CBIO	IC50	=	0.027	uM	ALA4221094	7.57		nM	Homo sapiens
8.	6-chloro-1,2-benzoxazol-3-ol	CBIO	Potency		3.548	uM	ALA1614211		inactive	nM	Homo sapiens
9.	6-chloro-1,2-benzoxazol-3-ol	CBIO	Potency		9.285	uM	ALA1794345		inactive	nM	Plasmodium falciparum
10.	6-chloro-1,2-benzoxazol-3-ol	CBIO	CL	=	10	ml/min.kg	ALA1832573			mL.min-1.kg-1	Mus musculus
11.	6-chloro-1,2-benzoxazol-3-ol	CBIO	CL	=	5	ml/min.kg	ALA1832396			mL.min-1.kg-1	Rattus norvegicus
12.	6-chloro-1,2-benzoxazol-3-ol	CBIO	Vd	=	0.2	L/Kg	ALA1832394			L.kg-1	Mus musculus
13.	6-chloro-1,2-benzoxazol-3-ol	CBIO	Vd	=	0.3	L/Kg	ALA1832392			L.kg-1	Rattus norvegicus
14.	6-chloro-1,2-benzoxazol-3-ol	CBIO	beta t1/2	=	1	hr	ALA1832390			hr	Mus musculus
15.	6-chloro-1,2-benzoxazol-3-ol	CBIO	beta t1/2	=	2	hr	ALA1832388			hr	Rattus norvegicus
16.	6-chloro-1,2-benzoxazol-3-ol	CBIO	Tmax	=	0.25	hr	ALA1832386			hr	Mus musculus
17.	6-chloro-1,2-benzoxazol-3-ol	CBIO	Tmax	=	0.5	hr	ALA1832384			hr	Rattus norvegicus
18.	6-chloro-1,2-benzoxazol-3-ol	CBIO	F	=	29	%	ALA1832281			%	Mus musculus
19.	6-chloro-1,2-benzoxazol-3-ol	CBIO	F	=	28	%	ALA1832279			%	Rattus norvegicus
20.	6-chloro-1,2-benzoxazol-3-ol	CBIO	BPR	=	0.03		ALA1832277