| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA466624 | 4a | IC50 | > | 5 | uM | ALA1653946 | nM | Homo sapiens | |||
| 2. | ALA466624 | 4a | IC50 | > | 5 | uM | ALA1653945 | nM | Homo sapiens | |||
| 3. | ALA466624 | 4a | IC50 | > | 5 | uM | ALA1653944 | nM | Homo sapiens | |||
| 4. | ALA466624 | 4a | IC50 | > | 5 | uM | ALA1653943 | nM | Homo sapiens | |||
| 5. | ALA466624 | 4a | IC50 | > | 5 | uM | ALA1653942 | nM | Homo sapiens | |||
| 6. | ALA466624 | 4a | solubility | > | 47 | ug ml-1 | ALA1653936 | ug.mL-1 | ||||
| 7. | ALA466624 | 4a | CL | < | 4.2 | ml/min.Kg | ALA1653941 | mL.min-1.kg-1 | Homo sapiens | |||
| 8. | ALA466624 | 4a | CL | < | 4.2 | ml/min.Kg | ALA1653939 | mL.min-1.kg-1 | Homo sapiens | |||
| 9. | ALA466624 | 4a | CL | < | 11 | ml/min.Kg | ALA1653940 | mL.min-1.kg-1 | Rattus norvegicus | |||
| 10. | ALA466624 | 4a | CL | < | 11 | ml/min.Kg | ALA1653938 | mL.min-1.kg-1 | Rattus norvegicus | |||
| 11. | ALA466624 | 4a | PPB | = | 47.7 | % | ALA1653948 | % | Mus musculus | |||
| 12. | ALA466624 | 4a | PPB | = | 23.3 | % | ALA1653947 | % | Homo sapiens | |||
| 13. | ALA466624 | 4a | permeability | = | 0 | 10'-6 cm/s | ALA1653937 | 10'-6 cm/s | ||||
| 14. | ALA466624 | 4a | Ratio | 0 | ALA1653935 | Not Determined | Homo sapiens | |||||
| 15. | ALA466624 | 4a | Ratio | = | 0.19 | ALA1653934 | Trypanosoma brucei brucei (strain 927/4 GUTat10.1) | |||||
| 16. | ALA466624 | 4a | IC50 | = | 0.172 | uM | ALA1653933 | 6.76 | nM | Trypanosoma brucei rhodesiense | ||
| 17. | ALA466624 | 4a | Cmax | = | 30 | ng/ml | ALA1654088 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Mus musculus | ||
| 18. | ALA466624 | 4a | Cmax | = | 33000 | ng/ml | ALA1654087 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Mus musculus | ||
| 19. | ALA466624 | 4a | Ratio AUC | = | 0.86 | ALA1654086 | ||||||
| 20. | ALA466624 | 4a | AUC | = | 0.14 | ug.hr/ml | ALA1654084 | ng.hr.mL-1 | Mus musculus |
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