Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	ALA443705	4b	IC50	>	5	uM	ALA1653946			nM	Homo sapiens
2.	ALA443705	4b	IC50	>	5	uM	ALA1653945			nM	Homo sapiens
3.	ALA443705	4b	IC50	>	5	uM	ALA1653944			nM	Homo sapiens
4.	ALA443705	4b	IC50	>	5	uM	ALA1653943			nM	Homo sapiens
5.	ALA443705	4b	IC50	>	5	uM	ALA1653942			nM	Homo sapiens
6.	ALA443705	4b	solubility	>	47	ug ml-1	ALA1653936			ug.mL-1
7.	ALA443705	4b	CL	<	4.2	ml/min.Kg	ALA1653941			mL.min-1.kg-1	Homo sapiens
8.	ALA443705	4b	CL	<	4.2	ml/min.Kg	ALA1653939			mL.min-1.kg-1	Homo sapiens
9.	ALA443705	4b	CL	<	11	ml/min.Kg	ALA1653940			mL.min-1.kg-1	Rattus norvegicus
10.	ALA443705	4b	CL	<	11	ml/min.Kg	ALA1653938			mL.min-1.kg-1	Rattus norvegicus
11.	ALA443705	4b	PPB	=	37.2	%	ALA1653948			%	Mus musculus
12.	ALA443705	4b	PPB	=	32.2	%	ALA1653947			%	Homo sapiens
13.	ALA443705	4b	permeability	=	0	10'-6 cm/s	ALA1653937			10'-6 cm/s
14.	ALA443705	4b	Ratio		0		ALA1653935		Not Determined		Homo sapiens
15.	ALA443705	4b	IC50	=	0.319	uM	ALA1653933	6.50		nM	Trypanosoma brucei rhodesiense
16.	ALA443705	4b	Ratio	=	0.19		ALA1653934				Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
17.	ALA443705	4b	IC50	>	14	uM	ALA971401			nM	Trypanosoma brucei brucei
18.	ALA443705	4b	IC50	=	2.6	uM	ALA971400	5.58		nM	Trypanosoma brucei rhodesiense
19.	ALA443705	4b	Ratio	=	0.19		ALA971399