| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA467047 | 7d | IC50 | > | 5 | uM | ALA1653946 | nM | Homo sapiens | |||
| 2. | ALA467047 | 7d | IC50 | > | 5 | uM | ALA1653945 | nM | Homo sapiens | |||
| 3. | ALA467047 | 7d | IC50 | > | 5 | uM | ALA1653944 | nM | Homo sapiens | |||
| 4. | ALA467047 | 7d | IC50 | > | 5 | uM | ALA1653943 | nM | Homo sapiens | |||
| 5. | ALA467047 | 7d | IC50 | > | 5 | uM | ALA1653942 | nM | Homo sapiens | |||
| 6. | ALA467047 | 7d | solubility | > | 49 | ug ml-1 | ALA1653936 | ug.mL-1 | ||||
| 7. | ALA467047 | 7d | CL | < | 4.2 | ml/min.Kg | ALA1653941 | mL.min-1.kg-1 | Homo sapiens | |||
| 8. | ALA467047 | 7d | CL | < | 4.2 | ml/min.Kg | ALA1653939 | mL.min-1.kg-1 | Homo sapiens | |||
| 9. | ALA467047 | 7d | CL | < | 11 | ml/min.Kg | ALA1653940 | mL.min-1.kg-1 | Rattus norvegicus | |||
| 10. | ALA467047 | 7d | CL | < | 11 | ml/min.Kg | ALA1653938 | mL.min-1.kg-1 | Rattus norvegicus | |||
| 11. | ALA467047 | 7d | PPB | = | 41.2 | % | ALA1653947 | % | Homo sapiens | |||
| 12. | ALA467047 | 7d | PPB | = | 35.7 | % | ALA1653948 | % | Mus musculus | |||
| 13. | ALA467047 | 7d | permeability | = | 0.22 | 10'-6 cm/s | ALA1653937 | 10'-6 cm/s | ||||
| 14. | ALA467047 | 7d | Ratio | = | 9.7 | ALA1653935 | Homo sapiens | |||||
| 15. | ALA467047 | 7d | Ratio | = | 7.78 | ALA1653934 | Trypanosoma brucei brucei (strain 927/4 GUTat10.1) | |||||
| 16. | ALA467047 | 7d | IC50 | = | 0 | uM | ALA1653933 | 10.00 | nM | Trypanosoma brucei rhodesiense | ||
| 17. | ALA467047 | 7d | Tmax | = | 0.25 | hr | ALA1654074 | hr | Rattus norvegicus | |||
| 18. | ALA467047 | 7d | Cmax | = | 39 | ng/ml | ALA1654075 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
| 19. | ALA467047 | 7d | AUC | = | 681 | ng.hr/ml | ALA1654076 | ng.hr.mL-1 | Rattus norvegicus | |||
| 20. | ALA467047 | 7d | AUC | = | 49 | ng.hr/ml | ALA1654077 | ng.hr.mL-1 | Rattus norvegicus |
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