Activities

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Activities

Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	ALA466059	24f	pKa	=	2.55		ALA1930044
2.	ALA466059	24f	F	=	46.6	%	ALA972390			%	Rattus norvegicus
3.	ALA466059	24f	AUC	=	0.2	microg/hr/ml	ALA972389			ng.hr.mL-1	Rattus norvegicus
4.	ALA466059	24f	AUC	=	0.09	microg/hr/ml	ALA974359			ng.hr.mL-1	Rattus norvegicus
5.	ALA466059	24f	Vdss	=	23.7	L/Kg	ALA974358			L.kg-1	Rattus norvegicus
6.	ALA466059	24f	CL	=	111.8	ml/min.Kg	ALA974357			mL.min-1.kg-1	Rattus norvegicus
7.	ALA466059	24f	beta t1/2	=	7	hr	ALA974356			hr	Rattus norvegicus
8.	ALA466059	24f	Tmax	=	0.56	hr	ALA974355			hr	Rattus norvegicus
9.	ALA466059	24f	Cmax	=	0.58	ug ml-1	ALA974354		standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW	nM	Rattus norvegicus
10.	ALA466059	24f	INH	=	45	%	ALA974347			%	Rattus norvegicus
11.	ALA466059	24f	INH	>	98	%	ALA974345			%	Bos taurus
12.	ALA466059	24f	INH	>	98	%	ALA974346			%	Bos taurus
13.	ALA466059	24f	Ratio IC50	=	20000		ALA974342
14.	ALA466059	24f	Ki	=	0.19	nM	ALA972392	9.72		nM	Homo sapiens
15.	ALA466059	24f	IC50	>	1000	nM	ALA974353			nM	Homo sapiens
16.	ALA466059	24f	IC50	=	91	nM	ALA974352	7.04		nM	Homo sapiens
17.	ALA466059	24f	IC50	=	10	nM	ALA974351	8.00		nM	Homo sapiens
18.	ALA466059	24f	IC50	=	3025	nM	ALA974350	5.52		nM	Homo sapiens
19.	ALA466059	24f	IC50	=	18	nM	ALA974349	7.75		nM	Homo sapiens
20.	ALA466059	24f	IC50	=	0.2	nM	ALA974348	9.70		nM	Homo sapiens