Activities

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Activities

Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	ALA444433	4a	IC50	=	261	uM	ALA2321360			nM	Rattus norvegicus
2.	ALA444433	4a	IC50	=	119	nM	ALA1044832	6.92		nM	Homo sapiens
3.	ALA444433	4a	IC50	=	261	nM	ALA1044831	6.58		nM	Rattus norvegicus
4.	ALA444433	4a	AUC	=	935	ng.hr/ml	ALA1044835			ng.hr.mL-1	Rattus norvegicus
5.	ALA444433	4a	Cmax	=	360	ng/ml	ALA1044836		standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW	nM	Rattus norvegicus
6.	ALA444433	4a	F	=	90	%	ALA1044837			%	Rattus norvegicus
7.	ALA444433	4a	Stability	=	85	%	ALA1044833			%	Homo sapiens
8.	ALA444433	4a	Stability	=	75	%	ALA1044834			%	Rattus norvegicus
9.	ALA444433	4a	CL	=	16.6	ml/min.Kg	ALA1044838			mL.min-1.kg-1	Rattus norvegicus
10.	ALA444433	4a	Vbeta	=	2.06	L/Kg	ALA1044839			L.kg-1	Rattus norvegicus
11.	ALA444433	4a	beta t1/2	=	1.46	hr	ALA1044840			hr	Rattus norvegicus
12.	ALA444433	4a	Drug uptake	=	283	ng/g	ALA1015838			ng/g	Rattus norvegicus
13.	ALA444433	4a	Activity		0		ALA1015840		Active		Rattus norvegicus
14.	ALA444433	4a	Activity		0		ALA1015839		Active		Rattus norvegicus
15.	ALA444433	4a	Drug uptake	=	753	ng/g	ALA1015837			ng/g	Rattus norvegicus
16.	ALA444433	4a	Cp	=	112	ng/ml	ALA1015836			ng/ml	Rattus norvegicus
17.	ALA444433	4a	t1/2	=	6.4	hr	ALA1015835			hr	Rattus norvegicus
18.	ALA444433	4a	t1/2	=	5.6	hr	ALA1015834			hr	Rattus norvegicus
19.	ALA444433	4a	t1/2	=	5	hr	ALA1015833			hr	Rattus norvegicus
20.	ALA444433	4a	Ratio	=	3		ALA1015832