Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	ALA453539	SFTI-1 (dicyclic)	IC50	>	5000	nM	ALA4380411			nM	Homo sapiens
2.	ALA453539	SFTI-1 (dicyclic)	Ki	=	200	nM	ALA4372206	6.70		nM	Homo sapiens
3.	ALA453539	SFTI-1 (dicyclic)	Ki	=	0.017	nM	ALA4372205	10.77		nM
4.	ALA453539	SFTI-1 (dicyclic)	K	=	0.2	10'7/M/s	ALA4372202			10'7/M/s	Sus scrofa
5.	ALA453539	SFTI-1 (dicyclic)	K	=	0.5	10'-4/s	ALA4372201			10'-4/s	Sus scrofa
6.	ALA453539	SFTI-1 (dicyclic)	Ki	=	130000	nM	ALA4372184			nM	Homo sapiens
7.	ALA453539	SFTI-1 (dicyclic)	Ki	=	0.008	nM	ALA4156167			nM	Bos taurus
8.	ALA453539	SFTI-1 (dicyclic)	Ki	=	0.03	nM	ALA4156165	10.52		nM	Homo sapiens
9.	ALA453539	SFTI-1 (dicyclic)	Ki	=	4960	nM	ALA4156163	5.30		nM	Homo sapiens
10.	ALA453539	SFTI-1 (dicyclic)	Activity		0		ALA4001018		Not Active		Mus musculus
11.	ALA453539	SFTI-1 (dicyclic)	Ki	=	13	nM	ALA4001016	7.89		nM	Bos taurus
12.	ALA453539	SFTI-1 (dicyclic)	Ki	=	1	nM	ALA4001015	9.00		nM	Bos taurus
13.	ALA453539	SFTI-1 (dicyclic)	Ki	=	0.1	nM	ALA4001014	10.00		nM	Bos taurus
14.	ALA453539	SFTI-1 (dicyclic)	Ki	=	2.35	nM	ALA4001013	8.63		nM	Bos taurus
15.	ALA453539	SFTI-1 (dicyclic)	Stability	>	80	%	ALA4001008			%
16.	ALA453539	SFTI-1 (dicyclic)	Stability	>	80	%	ALA4001007			%
17.	ALA453539	SFTI-1 (dicyclic)	Activity		0		ALA4001005		Not Active		Mus musculus
18.	ALA453539	SFTI-1 (dicyclic)	Activity		0		ALA4001003		Non-Toxic		Homo sapiens
19.	ALA453539	SFTI-1 (dicyclic)	INH		0		ALA4001002		Active	%	Bos taurus
20.	ALA453539	SFTI-1 (dicyclic)	EC50		0		ALA5033291		Not Determined		Mus musculus