| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  estrone-3-sulphate | estrone-3-O-sulfamate (EMATE) | Activity | = | 117000 | /s/microM | ALA4424771 | /s/microM | ||||
| 2. | estrone-3-sulphate | estrone-3-O-sulfamate (EMATE) | Kcat | = | 409 | 10'5/s | ALA4424770 | 10'5/s | ||||
| 3. | estrone-3-sulphate | estrone-3-O-sulfamate (EMATE) | Vmax | = | 3.8 | microM/s | ALA4424769 | microM/s | ||||
| 4. | estrone-3-sulphate | estrone-3-O-sulfamate (EMATE) | Km | = | 351 | uM | ALA4424768 | nM | ||||
| 5. | estrone-3-sulphate | estrone-3-O-sulfamate (EMATE) | Drug metabolism | = | 100 | % | ALA4424766 | % | ||||
| 6. | estrone-3-sulphate | estrone-3-O-sulfamate (EMATE) | Stability | 0 | ALA4424765 | Stable | % | |||||
| 7. | estrone-3-sulphate | estrone-3-O-sulfamate (EMATE) | pIC50 | < | 4.7 | ALA4651403 | No. Measurements = 1 | nM | Severe acute respiratory syndrome coronavirus 2 | |||
| 8. | estrone-3-sulphate | estrone-3-O-sulfamate (EMATE) | IC50 | > | 0 | M | ALA4651403 | No. Measurements = 1 | nM | Severe acute respiratory syndrome coronavirus 2 | ||
| 9. | estrone-3-sulphate | estrone-3-O-sulfamate (EMATE) | Ratio | = | 6.7 | ALA3528696 | Homo sapiens | |||||
| 10. | estrone-3-sulphate | estrone-3-O-sulfamate (EMATE) | Ratio | = | 44 | ALA3528698 | Homo sapiens | |||||
| 11. | estrone-3-sulphate | estrone-3-O-sulfamate (EMATE) | Ratio | = | 2.2 | ALA3528699 | Homo sapiens | |||||
| 12. | estrone-3-sulphate | estrone-3-O-sulfamate (EMATE) | Drug uptake | 0 | ALA3541985 | Active | Bos taurus | |||||
| 13. | estrone-3-sulphate | estrone-3-O-sulfamate (EMATE) | Drug uptake | 0 | ALA3541987 | Active | Bos taurus | |||||
| 14. | estrone-3-sulphate | estrone-3-O-sulfamate (EMATE) | Km | = | 0.25 | uM | ALA3538497 | nM | Bos taurus | |||
| 15. | estrone-3-sulphate | estrone-3-O-sulfamate (EMATE) | Km | = | 46.6 | uM | ALA3538498 | nM | Bos taurus | |||
| 16. | estrone-3-sulphate | estrone-3-O-sulfamate (EMATE) | Vmax | = | 24.5 | pmol/mg/min | ALA3538497 | pmol/mg/min | Bos taurus | |||
| 17. | estrone-3-sulphate | estrone-3-O-sulfamate (EMATE) | Vmax | = | 375 | pmol/mg/min | ALA3538498 | pmol/mg/min | Bos taurus | |||
| 18. | estrone-3-sulphate | estrone-3-O-sulfamate (EMATE) | Km | = | 16.1 | uM | ALA3538499 | nM | Homo sapiens | |||
| 19. | estrone-3-sulphate | estrone-3-O-sulfamate (EMATE) | Vmax | = | 39.4 | pmol/mg/min | ALA3538499 | pmol/mg/min | Homo sapiens | |||
| 20. | estrone-3-sulphate | estrone-3-O-sulfamate (EMATE) | Drug uptake | 0 | ALA3538501 | Active | Bos taurus |
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