| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA509075 | 8a | IC50 | = | 47 | nM | ALA1008931 | 7.33 | nM | Homo sapiens | ||
| 2. | ALA509075 | 8a | IC50 | = | 36 | uM | ALA1008932 | 4.44 | nM | Homo sapiens | ||
| 3. | ALA509075 | 8a | Ki | = | 1.2 | nM | ALA1008930 | 8.92 | nM | Homo sapiens | ||
| 4. | ALA509075 | 8a | pKi | = | 8.7 | ALA995612 | 8.70 | nM | Homo sapiens | |||
| 5. | ALA509075 | 8a | pIC50 | = | 4.4 | ALA995611 | 4.40 | nM | Homo sapiens | |||
| 6. | ALA509075 | 8a | IC50 | = | 4.9 | nM | ALA955062 | 8.31 | nM | Homo sapiens | ||
| 7. | ALA509075 | 8a | pKa | = | 4.16 | ALA955061 | ||||||
| 8. | ALA509075 | 8a | logD | = | 1.8 | ALA995613 | ||||||
| 9. | ALA509075 | 8a | Activity | = | 81 | nM | ALA955060 | nM | Macaca mulatta | |||
| 10. | ALA509075 | 8a | Activity | = | 11.2 | uM | ALA955059 | uM | Rattus norvegicus | |||
| 11. | ALA509075 | 8a | CL | = | 10 | ml/min.kg | ALA995614 | mL.min-1.kg-1 | Homo sapiens | |||
| 12. | ALA509075 | 8a | F | = | 22.6 | % | ALA955058 | % | Macaca fascicularis | |||
| 13. | ALA509075 | 8a | AUC | = | 1904 | ng/mL.hr | ALA955057 | ng.hr.mL-1 | Macaca fascicularis | |||
| 14. | ALA509075 | 8a | Tmax | = | 0.5 | hr | ALA955056 | hr | Macaca fascicularis | |||
| 15. | ALA509075 | 8a | Cmax | = | 2039 | ng/ml | ALA955055 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Macaca fascicularis | ||
| 16. | ALA509075 | 8a | t1/2 | = | 1 | hr | ALA955054 | hr | Macaca fascicularis | |||
| 17. | ALA509075 | 8a | Vd | = | 1.8 | L/Kg | ALA955053 | L.kg-1 | Macaca fascicularis | |||
| 18. | ALA509075 | 8a | CL | = | 20.9 | ml/min.kg | ALA955052 | mL.min-1.kg-1 | Macaca fascicularis | |||
| 19. | ALA509075 | 8a | F | = | 2.4 | % | ALA955051 | % | Rattus norvegicus | |||
| 20. | ALA509075 | 8a | AUC | = | 63.3 | ng/mL.hr | ALA954001 | ng.hr.mL-1 | Rattus norvegicus |
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