| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA450471 | 8d | pIC50 | = | 4.8 | ALA995611 | 4.80 | nM | Homo sapiens | |||
| 2. | ALA450471 | 8d | pKi | = | 8.5 | ALA995612 | 8.50 | nM | Homo sapiens | |||
| 3. | ALA450471 | 8d | IC50 | = | 11 | nM | ALA955062 | 7.96 | nM | Homo sapiens | ||
| 4. | ALA450471 | 8d | logD | = | 2.1 | ALA995613 | ||||||
| 5. | ALA450471 | 8d | CL | = | 9.5 | ml/min.kg | ALA995614 | mL.min-1.kg-1 | Homo sapiens | |||
| 6. | ALA450471 | 8d | Activity | = | 100 | nM | ALA955060 | nM | Macaca mulatta | |||
| 7. | ALA450471 | 8d | Activity | = | 12.5 | uM | ALA955059 | uM | Rattus norvegicus | |||
| 8. | ALA450471 | 8d | F | = | 52.7 | % | ALA955058 | % | Macaca fascicularis | |||
| 9. | ALA450471 | 8d | AUC | = | 11097 | ng/mL.hr | ALA955057 | ng.hr.mL-1 | Macaca fascicularis | |||
| 10. | ALA450471 | 8d | Tmax | = | 0.63 | hr | ALA955056 | hr | Macaca fascicularis | |||
| 11. | ALA450471 | 8d | Cmax | = | 7874 | ng/ml | ALA955055 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Macaca fascicularis | ||
| 12. | ALA450471 | 8d | t1/2 | = | 7.5 | hr | ALA955054 | hr | Macaca fascicularis | |||
| 13. | ALA450471 | 8d | Vd | = | 4.9 | L/Kg | ALA955053 | L.kg-1 | Macaca fascicularis | |||
| 14. | ALA450471 | 8d | CL | = | 7.9 | ml/min.kg | ALA955052 | mL.min-1.kg-1 | Macaca fascicularis | |||
| 15. | ALA450471 | 8d | F | = | 3 | % | ALA955051 | % | Rattus norvegicus | |||
| 16. | ALA450471 | 8d | AUC | = | 131.8 | ng/mL.hr | ALA954001 | ng.hr.mL-1 | Rattus norvegicus | |||
| 17. | ALA450471 | 8d | Tmax | = | 0.25 | hr | ALA1005193 | hr | Rattus norvegicus | |||
| 18. | ALA450471 | 8d | Cmax | = | 149 | ng/ml | ALA1005192 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
| 19. | ALA450471 | 8d | t1/2 | = | 0.4 | hr | ALA1005191 | hr | Rattus norvegicus | |||
| 20. | ALA450471 | 8d | Vd | = | 1.3 | L/Kg | ALA1005190 | L.kg-1 | Rattus norvegicus |
The page will load shortly, Thanks for your patience!