# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA498010 | 4a | IC50 | = | 46 | nM | ALA2176141 | 7.34 | nM | Plasmodium falciparum | ||
2. | ALA498010 | 4a | IC50 | = | 72 | nM | ALA2176142 | 7.14 | nM | Plasmodium falciparum | ||
3. | ALA498010 | 4a | IC50 | = | 13 | nM | ALA2176143 | 7.89 | nM | Plasmodium falciparum | ||
4. | ALA498010 | 4a | IC50 | = | 14 | nM | ALA2176144 | 7.85 | nM | Plasmodium falciparum | ||
5. | ALA498010 | 4a | Ratio IC50 | = | 1.5 | ALA2176145 | Plasmodium falciparum | |||||
6. | ALA498010 | 4a | Ratio IC50 | = | 1.1 | ALA2176146 | Plasmodium falciparum | |||||
7. | ALA498010 | 4a | INH | = | 70 | % | ALA2176279 | % | Plasmodium falciparum | |||
8. | ALA498010 | 4a | t1/2 | = | 44 | min | ALA1015414 | hr | Rattus norvegicus | |||
9. | ALA498010 | 4a | Vd | = | 40 | L/Kg | ALA1015413 | L.kg-1 | Rattus norvegicus | |||
10. | ALA498010 | 4a | Activity | 0 | ALA1015406 | Not Determined | Plasmodium berghei | |||||
11. | ALA498010 | 4a | Activity | = | 99.5 | % | ALA1012861 | % | Plasmodium chabaudi | |||
12. | ALA498010 | 4a | TC50 | = | 19.6 | uM | ALA1012860 | uM | Homo sapiens | |||
13. | ALA498010 | 4a | TC50 | = | 17.3 | uM | ALA1012859 | uM | ||||
14. | ALA498010 | 4a | TC50 | = | 8.6 | uM | ALA1012858 | uM | Homo sapiens | |||
15. | ALA498010 | 4a | IC50 | = | 14 | nM | ALA1012856 | 7.85 | nM | Plasmodium falciparum | ||
16. | ALA498010 | 4a | IC50 | = | 9 | nM | ALA1012854 | 8.05 | nM | Plasmodium falciparum | ||
17. | ALA498010 | 4a | IC50 | = | 72 | nM | ALA1012852 | 7.14 | nM | Plasmodium falciparum | ||
18. | ALA498010 | 4a | IC50 | = | 3.7 | nM | ALA1012853 | 8.43 | nM | Plasmodium falciparum | ||
19. | ALA498010 | 4a | IC50 | = | 13 | nM | ALA1012855 | 7.89 | nM | Plasmodium falciparum | ||
20. | ALA498010 | 4a | TC50 | = | 8.6 | uM | ALA1012857 | uM | Mus musculus |