Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Assay	Assay Organism
1.	ALA505733	(+)-3c	t1/2	=	2.48	hr	ALA958877		hr	Macaca mulatta
2.	ALA505733	(+)-3c	Vdss	=	0.53	L/Kg	ALA959671		L.kg-1	Macaca mulatta
3.	ALA505733	(+)-3c	Vc	=	0.53	L/Kg	ALA959670		L.kg-1	Macaca mulatta
4.	ALA505733	(+)-3c	AUC	=	197	uM	ALA958876		uM	Macaca mulatta
5.	ALA505733	(+)-3c	Cmax	=	34.4	uM	ALA958875		nM	Macaca mulatta
6.	ALA505733	(+)-3c	F	=	38	%	ALA958870		%	Macaca mulatta
7.	ALA505733	(+)-3c	Concentration	=	1.4	uM	ALA825215		uM
8.	ALA505733	(+)-3c	Concentration	=	100	uM	ALA825216		uM
9.	ALA505733	(+)-3c	Concentration	=	300	uM	ALA877133		uM	Mus musculus
10.	ALA505733	(+)-3c	Toxicity	>	100	uM	ALA825561		uM
11.	ALA505733	(+)-3c	EC90	=	0.26	uM	ALA833157		uM
12.	ALA505733	(+)-3c	EC50	=	0.04	uM	ALA832311	7.40	nM
13.	ALA505733	(+)-3c	Selectivity	=	800		ALA849596
14.	ALA505733	(+)-3c	IC50	>	2	uM	ALA687756		nM	Homo sapiens
15.	ALA505733	(+)-3c	IC50	=	0.4	uM	ALA687759	6.40	nM	Homo sapiens
16.	ALA505733	(+)-3c	EC50	=	0.001	uM	ALA697839	9.30	nM
17.	ALA505733	(+)-3c	Selectivity	>	1500		ALA849596
18.	ALA505733	(+)-3c	IC50	>	10	uM	ALA687756		nM	Homo sapiens
19.	ALA505733	(+)-3c	IC50	>	30	uM	ALA687759		nM	Homo sapiens
20.	ALA505733	(+)-3c	EC50	=	0.02	uM	ALA697839	7.70	nM