# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA35505 | Dihydralazine | IC50 | = | 0.5 | mM | ALA5128987 | nM | Homo sapiens | |||
2. | ALA35505 | Dihydralazine | IC50 | = | 0.5 | mM | ALA5128986 | nM | ||||
3. | ALA35505 | Dihydralazine | pIC50 | < | 4.7 | ALA4651403 | No. Measurements = 1 | nM | Severe acute respiratory syndrome coronavirus 2 | |||
4. | ALA35505 | Dihydralazine | IC50 | > | 0 | M | ALA4651403 | No. Measurements = 1 | nM | Severe acute respiratory syndrome coronavirus 2 | ||
5. | ALA35505 | Dihydralazine | AC50 | 3.162 | uM | ALA3562146 | inactive | nM | ||||
6. | ALA35505 | Dihydralazine | AC50 | 2.239 | uM | ALA3562136 | inactive | nM | ||||
7. | ALA35505 | Dihydralazine | Ac50 | 3.162 | uM | ALA3562152 | inactive | uM | ||||
8. | ALA35505 | Dihydralazine | Ac50 | 15.849 | uM | ALA3561990 | inactive | uM | ||||
9. | ALA35505 | Dihydralazine | Ac50 | 2.239 | uM | ALA3562064 | inactive | uM | ||||
10. | ALA35505 | Dihydralazine | AC50 | 15.849 | uM | ALA3562119 | inactive | nM | ||||
11. | ALA35505 | Dihydralazine | IC50 | > | 1000 | uM | ALA3540573 | nM | Homo sapiens | |||
12. | ALA35505 | Dihydralazine | IC50 | > | 1000 | uM | ALA3540574 | nM | Rattus norvegicus | |||
13. | ALA35505 | Dihydralazine | fCmax | = | 0.645 | uM | ALA3540575 | uM | Homo sapiens | |||
14. | ALA35505 | Dihydralazine | Potency | 15.849 | uM | ALA3214913 | inactive | nM | ||||
15. | ALA35505 | Dihydralazine | IC50 | > | 1000 | uM | ALA4017550 | nM | Homo sapiens | |||
16. | ALA35505 | Dihydralazine | Hepatotoxicity (mechanism) | 0 | ALA3137740 | Allergic | ||||||
17. | ALA35505 | Dihydralazine | Hepatotoxicity (time to onset) | 0 | ALA3137739 | 2 days - 3 years | ||||||
18. | ALA35505 | Dihydralazine | Hepatotoxicity (comment) | 0 | ALA3137738 | AC_ANTI-MF/-M/-N/-CYP1A2 | ||||||
19. | ALA35505 | Dihydralazine | Hepatotoxicity (successful reintroduction) | 0 | ALA3137737 | yes | ||||||
20. | ALA35505 | Dihydralazine | Hepatotoxicity (animal toxicity known) | 0 | ALA3137736 |