| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  pyronaridine | (4) Pyronaridine | MIC | = | 5 | ug ml-1 | ALA5234133 | ug.mL-1 | Mycobacterium tuberculosis | |||
| 2. | pyronaridine | (4) Pyronaridine | INH | = | 31 | % | ALA5217444 | % | Homo sapiens | |||
| 3. | pyronaridine | (4) Pyronaridine | INH | = | 35 | % | ALA5217443 | % | Homo sapiens | |||
| 4. | pyronaridine | (4) Pyronaridine | IC50 | > | 10 | uM | ALA5217442 | nM | ||||
| 5. | pyronaridine | (4) Pyronaridine | IC50 | = | 3.1 | uM | ALA5217441 | 5.51 | nM | Homo sapiens | ||
| 6. | pyronaridine | (4) Pyronaridine | IC50 | = | 1.3 | uM | ALA5217440 | 5.89 | nM | Chlorocebus sabaeus | ||
| 7. | pyronaridine | (4) Pyronaridine | INH | > | 50 | % | ALA5217438 | % | Homo sapiens | |||
| 8. | pyronaridine | (4) Pyronaridine | Activity | 0 | ALA5217435 | NA | Homo sapiens | |||||
| 9. | pyronaridine | (4) Pyronaridine | Activity | 0 | ALA5217433 | NA | Homo sapiens | |||||
| 10. | pyronaridine | (4) Pyronaridine | IC50 | = | 4.23 | uM | ALA5217431 | 5.37 | nM | Homo sapiens | ||
| 11. | pyronaridine | (4) Pyronaridine | IC50 | = | 3.45 | uM | ALA5217430 | 5.46 | nM | Homo sapiens | ||
| 12. | pyronaridine | (4) Pyronaridine | IC50 | = | 1.7 | uM | ALA5217429 | 5.77 | nM | Homo sapiens | ||
| 13. | pyronaridine | (4) Pyronaridine | IC50 | = | 2.2 | uM | ALA5150570 | 5.66 | nM | Plasmodium falciparum | ||
| 14. | pyronaridine | (4) Pyronaridine | EC50 | = | 0.094 | uM | ALA5150534 | 7.03 | nM | Plasmodium falciparum | ||
| 15. | pyronaridine | (4) Pyronaridine | Ratio CC50/IC50 | = | 507 | ALA4372780 | ||||||
| 16. | pyronaridine | (4) Pyronaridine | GI | = | 95.6 | % | ALA4372779 | % | Homo sapiens | |||
| 17. | pyronaridine | (4) Pyronaridine | GI | = | 102 | % | ALA4372778 | % | Homo sapiens | |||
| 18. | pyronaridine | (4) Pyronaridine | CC50 | = | 3549.5 | nM | ALA4372777 | nM | Homo sapiens | |||
| 19. | pyronaridine | (4) Pyronaridine | IC50 | = | 7.9 | nM | ALA4372776 | 8.10 | nM | Plasmodium falciparum | ||
| 20. | pyronaridine | (4) Pyronaridine | IC50 | = | 7 | nM | ALA4372775 | 8.15 | nM | Plasmodium falciparum |
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