# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA416956 | Mefloquine | inhibition | = | 6.37 | % | ALA4808150 | % | Homo sapiens | |||
2. | ALA416956 | Mefloquine | inhibition | = | 15.67 | % | ALA4808149 | % | Homo sapiens | |||
3. | ALA416956 | Mefloquine | Hit score | = | -0.076 | ALA4303810 | Severe acute respiratory syndrome coronavirus 2 | |||||
4. | ALA416956 | Mefloquine | Selectivity index | = | 3.22 | ALA4303814 | ||||||
5. | ALA416956 | Mefloquine | CC50 | = | 13.97 | uM | ALA4303813 | nM | Chlorocebus sabaeus | |||
6. | ALA416956 | Mefloquine | IC50 | = | 4.33 | uM | ALA4303812 | 5.36 | nM | Severe acute respiratory syndrome coronavirus 2 | ||
7. | ALA416956 | Mefloquine | %max | = | 220 | % | ALA3423810 | % | Homo sapiens | |||
8. | ALA416956 | Mefloquine | EC50 | = | 2.5 | uM | ALA3423809 | 5.60 | nM | Homo sapiens | ||
9. | ALA416956 | Mefloquine | Activity | = | 126 | % | ALA3423808 | % | Homo sapiens | |||
10. | ALA416956 | Mefloquine | INH | = | 95 | % | ALA3423653 | % | Homo sapiens | |||
11. | ALA416956 | Mefloquine | IC50 | = | 65 | nM | ALA3417910 | 7.19 | nM | Plasmodium falciparum | ||
12. | ALA416956 | Mefloquine | IC50 | = | 55 | nM | ALA3417908 | 7.26 | nM | Plasmodium falciparum | ||
13. | ALA416956 | Mefloquine | IC50 | = | 20 | nM | ALA3417906 | 7.70 | nM | Plasmodium falciparum | ||
14. | ALA416956 | Mefloquine | IC50 | = | 14 | nM | ALA3417904 | 7.85 | nM | Plasmodium falciparum | ||
15. | ALA416956 | Mefloquine | IC50 | = | 7 | nM | ALA3405930 | 8.15 | nM | Plasmodium falciparum | ||
16. | ALA416956 | Mefloquine | IC50 | = | 23 | nM | ALA3405931 | 7.64 | nM | Plasmodium falciparum | ||
17. | ALA416956 | Mefloquine | IC50 | = | 55 | nM | ALA3405932 | 7.26 | nM | Plasmodium falciparum | ||
18. | ALA416956 | Mefloquine | Potency | 0.089 | uM | ALA3214970 | active | nM | ||||
19. | ALA416956 | Mefloquine | Potency | 0.067 | uM | ALA3214842 | inactive | nM | ||||
20. | ALA416956 | Mefloquine | Potency | 17.783 | uM | ALA3214913 | inconclusive | nM |