| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA503209 | 11o | F | = | 27.3 | % | ALA977235 | % | Rattus norvegicus | |||
| 2. | ALA503209 | 11o | Selectivity ratio | = | 12.8 | ALA977257 | ||||||
| 3. | ALA503209 | 11o | PB | = | 90 | % | ALA977256 | % | Canis lupus familiaris | |||
| 4. | ALA503209 | 11o | INH | = | 57 | % | ALA977255 | % | Canis lupus familiaris | |||
| 5. | ALA503209 | 11o | EC50 | = | 46 | nM | ALA977254 | 7.34 | nM | Canis lupus familiaris | ||
| 6. | ALA503209 | 11o | F | = | 76.8 | % | ALA977253 | % | Canis lupus familiaris | |||
| 7. | ALA503209 | 11o | F | = | 28.8 | % | ALA977238 | % | Macaca mulatta | |||
| 8. | ALA503209 | 11o | CL | = | 15.7 | ml/min.kg | ALA977237 | mL.min-1.kg-1 | Macaca mulatta | |||
| 9. | ALA503209 | 11o | CL | = | 3.1 | ml/min.kg | ALA977252 | mL.min-1.kg-1 | Canis lupus familiaris | |||
| 10. | ALA503209 | 11o | CL | = | 2.5 | ml/min.kg | ALA977234 | mL.min-1.kg-1 | Rattus norvegicus | |||
| 11. | ALA503209 | 11o | t1/2 | = | 15.3 | hr | ALA977233 | hr | Rattus norvegicus | |||
| 12. | ALA503209 | 11o | t1/2 | = | 5.9 | hr | ALA977251 | hr | Canis lupus familiaris | |||
| 13. | ALA503209 | 11o | t1/2 | = | 8.2 | hr | ALA977236 | hr | Macaca mulatta | |||
| 14. | ALA503209 | 11o | AUC | = | 1937 | ng.hr/ml | ALA976366 | ng.hr.mL-1 | Rattus norvegicus | |||
| 15. | ALA503209 | 11o | AUC | = | 860.1 | ng.hr/ml | ALA974629 | ng.hr.mL-1 | Canis lupus familiaris | |||
| 16. | ALA503209 | 11o | AUC | = | 313 | ng.hr/ml | ALA976362 | ng.hr.mL-1 | Macaca mulatta | |||
| 17. | ALA503209 | 11o | Cmax | = | 59 | ng/ml | ALA976361 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Macaca mulatta | ||
| 18. | ALA503209 | 11o | Cmax | = | 64.4 | ng/ml | ALA974628 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Canis lupus familiaris | ||
| 19. | ALA503209 | 11o | Cmax | = | 164 | ng/ml | ALA976365 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
| 20. | ALA503209 | 11o | Intrinsic activity | = | 0.89 | ALA974623 | Homo sapiens |
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