| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA514102 | 12b | Selectivity ratio | = | 65.8 | ALA977257 | ||||||
| 2. | ALA514102 | 12b | PB | = | 97 | % | ALA977256 | % | Canis lupus familiaris | |||
| 3. | ALA514102 | 12b | INH | = | 33 | % | ALA977255 | % | Canis lupus familiaris | |||
| 4. | ALA514102 | 12b | EC50 | = | 25 | nM | ALA977254 | 7.60 | nM | Canis lupus familiaris | ||
| 5. | ALA514102 | 12b | F | = | 63.4 | % | ALA977232 | % | Rattus norvegicus | |||
| 6. | ALA514102 | 12b | F | > | 95 | % | ALA977253 | % | Canis lupus familiaris | |||
| 7. | ALA514102 | 12b | F | = | 81.7 | % | ALA977238 | % | Macaca mulatta | |||
| 8. | ALA514102 | 12b | CL | = | 11.4 | ml/min.kg | ALA976381 | mL.min-1.kg-1 | Rattus norvegicus | |||
| 9. | ALA514102 | 12b | CL | = | 1.7 | ml/min.kg | ALA977252 | mL.min-1.kg-1 | Canis lupus familiaris | |||
| 10. | ALA514102 | 12b | CL | = | 6.7 | ml/min.kg | ALA977237 | mL.min-1.kg-1 | Macaca mulatta | |||
| 11. | ALA514102 | 12b | t1/2 | = | 13.6 | hr | ALA976380 | hr | Rattus norvegicus | |||
| 12. | ALA514102 | 12b | t1/2 | = | 14.3 | hr | ALA977251 | hr | Canis lupus familiaris | |||
| 13. | ALA514102 | 12b | t1/2 | = | 7.7 | hr | ALA977236 | hr | Macaca mulatta | |||
| 14. | ALA514102 | 12b | AUC | = | 470 | ng.hr/ml | ALA976370 | ng.hr.mL-1 | Rattus norvegicus | |||
| 15. | ALA514102 | 12b | AUC | = | 1980 | ng.hr/ml | ALA974629 | ng.hr.mL-1 | Canis lupus familiaris | |||
| 16. | ALA514102 | 12b | AUC | = | 722 | ng.hr/ml | ALA976372 | ng.hr.mL-1 | Macaca mulatta | |||
| 17. | ALA514102 | 12b | Cmax | = | 91.2 | ng/ml | ALA976371 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Macaca mulatta | ||
| 18. | ALA514102 | 12b | Cmax | = | 113 | ng/ml | ALA974628 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Canis lupus familiaris | ||
| 19. | ALA514102 | 12b | Cmax | = | 65 | ng/ml | ALA976369 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
| 20. | ALA514102 | 12b | Intrinsic activity | = | 1.02 | ALA974623 | Homo sapiens |
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