# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA455912 | 10d | IC50 | < | 1 | nM | ALA997028 | nM | Homo sapiens | |||
2. | ALA455912 | 10d | AUC | = | 916 | nM.hr | ALA997038 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | Rattus norvegicus | ||
3. | ALA455912 | 10d | IC50 | = | 44 | nM | ALA997029 | 7.36 | nM | Homo sapiens | ||
4. | ALA455912 | 10d | CL | = | 1 | L/hr/kg | ALA997033 | mL.min-1.kg-1 | Rattus norvegicus | |||
5. | ALA455912 | 10d | solubility | = | 27 | mg/L | ALA997032 | ug.mL-1 | ||||
6. | ALA455912 | 10d | IC50 | = | 150 | nM | ALA997030 | 6.82 | nM | Homo sapiens | ||
7. | ALA455912 | 10d | t1/2 | = | 5.7 | hr | ALA997035 | hr | Rattus norvegicus | |||
8. | ALA455912 | 10d | F | = | 42 | % | ALA997036 | % | Rattus norvegicus | |||
9. | ALA455912 | 10d | Selectivity ratio | > | 100 | ALA997031 | ||||||
10. | ALA455912 | 10d | Activity | 0 | ALA997039 | Active | Mus musculus |