Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	ALA455907	(S)-33a	Activity	=	6	%	ALA1013590			%	Homo sapiens
2.	ALA455907	(S)-33a	Fu	=	10.8	%	ALA1016216				Macaca fascicularis
3.	ALA455907	(S)-33a	Cp	=	26	uM	ALA1016218			uM	Macaca fascicularis
4.	ALA455907	(S)-33a	Cp	=	4.9	uM	ALA1016217			uM	Macaca fascicularis
5.	ALA455907	(S)-33a	Activity		0		ALA1016220		Active		Macaca fascicularis
6.	ALA455907	(S)-33a	Activity		0		ALA1016219		Active		Macaca fascicularis
7.	ALA455907	(S)-33a	Vdss	=	1.4	L/Kg	ALA1013604			L.kg-1	Mus musculus
8.	ALA455907	(S)-33a	CL	=	0.31	L/hr/kg	ALA1013608			mL.min-1.kg-1	Rattus norvegicus
9.	ALA455907	(S)-33a	CL	=	0.085	L/hr/kg	ALA1013613			mL.min-1.kg-1	Canis lupus familiaris
10.	ALA455907	(S)-33a	CL	=	1.6	L/hr/kg	ALA1013603			mL.min-1.kg-1	Mus musculus
11.	ALA455907	(S)-33a	IC50	=	42	nM	ALA1013602	7.38		nM
12.	ALA455907	(S)-33a	IC50	=	45	nM	ALA1013601	7.35		nM	Canis lupus familiaris
13.	ALA455907	(S)-33a	IC50	=	340	nM	ALA1013600	6.47		nM	Rattus norvegicus
14.	ALA455907	(S)-33a	IC50	=	140	nM	ALA1013599	6.85		nM	Mus musculus
15.	ALA455907	(S)-33a	Ki	=	48	nM	ALA1013598	7.32		nM
16.	ALA455907	(S)-33a	Ki	=	12	nM	ALA1013597	7.92		nM	Canis lupus familiaris
17.	ALA455907	(S)-33a	Ki	=	300	nM	ALA1013596	6.52		nM	Rattus norvegicus
18.	ALA455907	(S)-33a	Ki	=	100	nM	ALA1013595	7.00		nM	Mus musculus
19.	ALA455907	(S)-33a	Activity	=	10	%	ALA1013594			%	Homo sapiens
20.	ALA455907	(S)-33a	Activity	=	17	%	ALA1013593			%	Homo sapiens