# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA475306 | 12-3, BMS-561388 | IC50 | = | 4.2 | nM | ALA1811340 | 8.38 | nM | Rattus norvegicus | ||
2. | ALA475306 | 12-3, BMS-561388 | F | = | 51 | % | ALA985753 | % | Rattus norvegicus | |||
3. | ALA475306 | 12-3, BMS-561388 | Cmax | = | 0.851 | uM | ALA985752 | nM | Rattus norvegicus | |||
4. | ALA475306 | 12-3, BMS-561388 | Tmax | = | 0.5 | hr | ALA985751 | hr | Rattus norvegicus | |||
5. | ALA475306 | 12-3, BMS-561388 | beta t1/2 | = | 9.7 | hr | ALA985749 | hr | Rattus norvegicus | |||
6. | ALA475306 | 12-3, BMS-561388 | beta t1/2 | = | 11.9 | hr | ALA985750 | hr | Rattus norvegicus | |||
7. | ALA475306 | 12-3, BMS-561388 | QH | = | 3.3 | L/hr.Kg | ALA1006263 | L/hr.Kg | Rattus norvegicus | |||
8. | ALA475306 | 12-3, BMS-561388 | QH | = | 3.3 | L/hr.Kg | ALA985754 | L/hr.Kg | Rattus norvegicus | |||
9. | ALA475306 | 12-3, BMS-561388 | CL | = | 0.87 | L/hr.Kg | ALA985748 | mL.min-1.kg-1 | Rattus norvegicus | |||
10. | ALA475306 | 12-3, BMS-561388 | CL | = | 1.2 | L/hr.Kg | ALA985747 | mL.min-1.kg-1 | Rattus norvegicus | |||
11. | ALA475306 | 12-3, BMS-561388 | Vdss | = | 12.2 | L/Kg | ALA985746 | L.kg-1 | Rattus norvegicus | |||
12. | ALA475306 | 12-3, BMS-561388 | Vdss | = | 14.6 | L/Kg | ALA985745 | L.kg-1 | Rattus norvegicus | |||
13. | ALA475306 | 12-3, BMS-561388 | Time | = | 158 | s | ALA985744 | hr | Rattus norvegicus | |||
14. | ALA475306 | 12-3, BMS-561388 | Activity | = | 4986 | cm | ALA985743 | cm | Rattus norvegicus | |||
15. | ALA475306 | 12-3, BMS-561388 | MED | = | 3 | mg kg-1 | ALA1006264 | mg kg-1 | Rattus norvegicus | |||
16. | ALA475306 | 12-3, BMS-561388 | Activity | = | 82 | % | ALA985742 | % | Rattus norvegicus | |||
17. | ALA475306 | 12-3, BMS-561388 | Activity | = | 48 | % | ALA985740 | % | Rattus norvegicus | |||
18. | ALA475306 | 12-3, BMS-561388 | Activity | = | 60 | % | ALA985741 | % | Rattus norvegicus | |||
19. | ALA475306 | 12-3, BMS-561388 | Activity | = | 62 | % | ALA985736 | % | Rattus norvegicus | |||
20. | ALA475306 | 12-3, BMS-561388 | Activity | 0 | ALA985734 | Active | Rattus norvegicus |