| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA445481 | 7e | Ratio EC50 | > | 50 | ALA1003000 | ||||||
| 2. | ALA445481 | 7e | EC50 | = | 62 | nM | ALA1002998 | 7.21 | nM | |||
| 3. | ALA445481 | 7e | PPB | = | 83 | % | ALA1002999 | % | Canis lupus familiaris | |||
| 4. | ALA445481 | 7e | EC50 | = | 26.5 | nM | ALA1007111 | 7.58 | nM | Canis lupus familiaris | ||
| 5. | ALA445481 | 7e | ED50 | = | 16.2 | ug/kg | ALA1007111 | mg.kg-1 | Canis lupus familiaris | |||
| 6. | ALA445481 | 7e | INH | > | 70 | % | ALA1007109 | % | Canis lupus familiaris | |||
| 7. | ALA445481 | 7e | EC50 | = | 1.4 | nM | ALA1007108 | 8.85 | nM | Canis lupus familiaris | ||
| 8. | ALA445481 | 7e | EC50 | = | 800 | nM | ALA1007085 | 6.10 | nM | Homo sapiens | ||
| 9. | ALA445481 | 7e | EC50 | > | 10000 | nM | ALA1007086 | nM | Homo sapiens | |||
| 10. | ALA445481 | 7e | EC50 | = | 0.13 | nM | ALA1007087 | 9.89 | nM | Homo sapiens | ||
| 11. | ALA445481 | 7e | Cmax | = | 34.5 | ng/ml | ALA1007089 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Canis lupus familiaris | ||
| 12. | ALA445481 | 7e | AUC | = | 384.6 | ng.hr/ml | ALA1007090 | ng.hr.mL-1 | Canis lupus familiaris | |||
| 13. | ALA445481 | 7e | beta t1/2 | = | 5.5 | hr | ALA1007091 | hr | Canis lupus familiaris | |||
| 14. | ALA445481 | 7e | CL | = | 3.2 | ml/min.kg | ALA1007092 | mL.min-1.kg-1 | Canis lupus familiaris | |||
| 15. | ALA445481 | 7e | F | = | 81 | % | ALA1007093 | % | Canis lupus familiaris | |||
| 16. | ALA445481 | 7e | CL | = | 46.9 | ml/min.kg | ALA1007094 | mL.min-1.kg-1 | Rattus norvegicus | |||
| 17. | ALA445481 | 7e | CL | = | 5.4 | ml/min.kg | ALA1007095 | mL.min-1.kg-1 | ||||
| 18. | ALA445481 | 7e | CL | = | 3.4 | ml/min.kg | ALA1007096 | mL.min-1.kg-1 | ||||
| 19. | ALA445481 | 7e | CL | = | 2.2 | ml/min.kg | ALA1007097 | mL.min-1.kg-1 | Homo sapiens | |||
| 20. | ALA445481 | 7e | AUC | = | 72.2 | ng.hr/ml | ALA1007099 | ng.hr.mL-1 | Rattus norvegicus |
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