| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA1686 | alpha-ketoglutarate | EC50 | = | 54 | uM | ALA5209627 | 4.27 | Substrate | nM | Homo sapiens | |
| 2. | ALA1686 | alpha-ketoglutarate | inhibition | = | -15.93 | % | ALA4808150 | % | Homo sapiens | |||
| 3. | ALA1686 | alpha-ketoglutarate | inhibition | = | 24.56 | % | ALA4808149 | % | Homo sapiens | |||
| 4. | ALA1686 | alpha-ketoglutarate | IC50 | = | 250 | uM | ALA4719877 | nM | ||||
| 5. | ALA1686 | alpha-ketoglutarate | Ki | = | 83 | uM | ALA4719877 | 4.08 | nM | |||
| 6. | ALA1686 | alpha-ketoglutarate | Inhibition | = | 15.59 | % | ALA4303805 | % | Severe acute respiratory syndrome coronavirus 2 | |||
| 7. | ALA1686 | alpha-ketoglutarate | pIC50 | < | 4.7 | ALA4651403 | No. Measurements = 1 | nM | Severe acute respiratory syndrome coronavirus 2 | |||
| 8. | ALA1686 | alpha-ketoglutarate | IC50 | > | 0 | M | ALA4651403 | No. Measurements = 1 | nM | Severe acute respiratory syndrome coronavirus 2 | ||
| 9. | ALA1686 | alpha-ketoglutarate | inhibition | = | 0.21 | % | ALA4513082 | % | Severe acute respiratory syndrome coronavirus 2 | |||
| 10. | ALA1686 | alpha-ketoglutarate | IC50 | = | 800 | uM | ALA4613338 | nM | Homo sapiens | |||
| 11. | ALA1686 | alpha-ketoglutarate | Km | = | 0.2 | mM | ALA2317655 | nM | ||||
| 12. | ALA1686 | alpha-ketoglutarate | Kcat | = | 39.6 | /s | ALA2317655 | /s | ||||
| 13. | ALA1686 | alpha-ketoglutarate | Kcat | = | 100 | % | ALA2317654 | % | ||||
| 14. | ALA1686 | alpha-ketoglutarate | Kd | = | 900 | nM | ALA2318595 | 6.05 | nM | Homo sapiens | ||
| 15. | ALA1686 | alpha-ketoglutarate | Kd | < | 2 | uM | ALA2318594 | nM | Homo sapiens | |||
| 16. | ALA1686 | alpha-ketoglutarate | Potency | 66.824 | uM | ALA2114890 | inconclusive | nM | Homo sapiens | |||
| 17. | ALA1686 | alpha-ketoglutarate | Activity | 0 | ALA2077864 | inhibitor [(at a rough estimate) 5 % of control] | Homo sapiens | |||||
| 18. | ALA1686 | alpha-ketoglutarate | Activity | 0 | ALA2077170 | inhibitor [(at a rough estimate) 35 % of control] | Homo sapiens | |||||
| 19. | ALA1686 | alpha-ketoglutarate | Activity | 0 | ALA2076627 | inhibitor [(at a rough estimate) 10 % of control] | Mus musculus | |||||
| 20. | ALA1686 | alpha-ketoglutarate | Activity | 0 | ALA2078097 | is not an inhibitor [-] | Homo sapiens |
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