Activities

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Activities

Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	ALA1686	alpha-ketoglutarate	EC50	=	54	uM	ALA5209627	4.27	Substrate	nM	Homo sapiens
2.	ALA1686	alpha-ketoglutarate	Inhibition	=	15.59	%	ALA4303805			%	Severe acute respiratory syndrome coronavirus 2
3.	ALA1686	alpha-ketoglutarate	inhibition	=	-15.93	%	ALA4808150			%	Homo sapiens
4.	ALA1686	alpha-ketoglutarate	inhibition	=	24.56	%	ALA4808149			%	Homo sapiens
5.	ALA1686	alpha-ketoglutarate	IC50	=	250	uM	ALA4719877			nM
6.	ALA1686	alpha-ketoglutarate	Ki	=	83	uM	ALA4719877	4.08		nM
7.	ALA1686	alpha-ketoglutarate	pIC50	<	4.7		ALA4651403		No. Measurements = 1	nM	Severe acute respiratory syndrome coronavirus 2
8.	ALA1686	alpha-ketoglutarate	IC50	>	0	M	ALA4651403		No. Measurements = 1	nM	Severe acute respiratory syndrome coronavirus 2
9.	ALA1686	alpha-ketoglutarate	inhibition	=	0.21	%	ALA4513082			%	Severe acute respiratory syndrome coronavirus 2
10.	ALA1686	alpha-ketoglutarate	IC50	=	800	uM	ALA4613338			nM	Homo sapiens
11.	ALA1686	alpha-ketoglutarate	inhibition	=	0.21	%	ALA4513082			%	Severe acute respiratory syndrome coronavirus 2
12.	ALA1686	alpha-ketoglutarate	Inhibition	=	7.338	%	ALA4495582			%	Severe acute respiratory syndrome coronavirus 2
13.	ALA1686	alpha-ketoglutarate	EC50	=	5.5	10'-9M	ALA4482521	8.26		nM	Homo sapiens
14.	ALA1686	alpha-ketoglutarate	Ratio	=	0.594		ALA4482522				Homo sapiens
15.	ALA1686	alpha-ketoglutarate	Km	=	0.2	mM	ALA2317655			nM
16.	ALA1686	alpha-ketoglutarate	Kcat	=	39.6	/s	ALA2317655			/s
17.	ALA1686	alpha-ketoglutarate	Kcat	=	100	%	ALA2317654			%
18.	ALA1686	alpha-ketoglutarate	Kd	=	900	nM	ALA2318595	6.05		nM	Homo sapiens
19.	ALA1686	alpha-ketoglutarate	Kd	<	2	uM	ALA2318594			nM	Homo sapiens
20.	ALA1686	alpha-ketoglutarate	Potency		66.824	uM	ALA2114890		inconclusive	nM	Homo sapiens