| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA469821 | 6j | EC50 | = | 2.6 | nM | ALA1002998 | 8.59 | nM | |||
| 2. | ALA469821 | 6j | PPB | = | 92 | % | ALA1002999 | % | Canis lupus familiaris | |||
| 3. | ALA469821 | 6j | EC50 | = | 14.2 | nM | ALA1007111 | 7.85 | nM | Canis lupus familiaris | ||
| 4. | ALA469821 | 6j | ED50 | = | 24.7 | ug/kg | ALA1007111 | mg.kg-1 | Canis lupus familiaris | |||
| 5. | ALA469821 | 6j | INH | > | 70 | % | ALA1007109 | % | Canis lupus familiaris | |||
| 6. | ALA469821 | 6j | EC50 | = | 0.88 | nM | ALA1007108 | 9.06 | nM | Canis lupus familiaris | ||
| 7. | ALA469821 | 6j | EC50 | > | 1000 | nM | ALA1007085 | nM | Homo sapiens | |||
| 8. | ALA469821 | 6j | EC50 | > | 10000 | nM | ALA1007086 | nM | Homo sapiens | |||
| 9. | ALA469821 | 6j | EC50 | = | 0.46 | nM | ALA1007087 | 9.34 | nM | Homo sapiens | ||
| 10. | ALA469821 | 6j | Cmax | = | 24.9 | ng/ml | ALA1007089 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Canis lupus familiaris | ||
| 11. | ALA469821 | 6j | AUC | = | 210.5 | ng.hr/ml | ALA1007090 | ng.hr.mL-1 | Canis lupus familiaris | |||
| 12. | ALA469821 | 6j | beta t1/2 | = | 3.5 | hr | ALA1007091 | hr | Canis lupus familiaris | |||
| 13. | ALA469821 | 6j | CL | = | 5.3 | ml/min.kg | ALA1007092 | mL.min-1.kg-1 | Canis lupus familiaris | |||
| 14. | ALA469821 | 6j | F | = | 67 | % | ALA1007093 | % | Canis lupus familiaris | |||
| 15. | ALA469821 | 6j | CL | 0 | ALA1007094 | Not Determined | Rattus norvegicus | |||||
| 16. | ALA469821 | 6j | CL | 0 | ALA1007095 | Not Determined | ||||||
| 17. | ALA469821 | 6j | CL | 0 | ALA1007096 | Not Determined | ||||||
| 18. | ALA469821 | 6j | CL | 0 | ALA1007097 | Not Determined | Homo sapiens | |||||
| 19. | ALA469821 | 6j | Cmax | = | 6.4 | ng/ml | ALA1007098 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
| 20. | ALA469821 | 6j | AUC | = | 64.8 | ng.hr/ml | ALA1007099 | ng.hr.mL-1 | Rattus norvegicus |
The page will load shortly, Thanks for your patience!