| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA530275 | TCMDC-125825 | Solubility | = | 302 | uM | ALA2098499 | nM | ||||
| 2. | ALA530275 | TCMDC-125825 | logP | = | 6.74 | ALA2098498 | ||||||
| 3. | ALA530275 | TCMDC-125825 | logD7.4 | = | 6.09 | ALA2098497 | ||||||
| 4. | ALA530275 | TCMDC-125825 | MIC90 | = | 7.079 | uM | ALA2098496 | nM | Mycobacterium tuberculosis H37Rv | |||
| 5. | ALA530275 | TCMDC-125825 | MIC90 | = | 3.7 | uM | ALA2098495 | nM | Mycobacterium tuberculosis variant bovis BCG | |||
| 6. | ALA530275 | TCMDC-125825 | CC50 | > | 10 | uM | ALA4296191 | Median N= 2; Maxinhib 20.6 Pct | nM | Homo sapiens | ||
| 7. | ALA530275 | TCMDC-125825 | HC10 | > | 10 | uM | ALA4296784 | Median N= 2; Maxinhib 0.4 Pct | uM | |||
| 8. | ALA530275 | TCMDC-125825 | MIC | = | 10 | uM | ALA4296184 | Median N= 2 | nM | Staphylococcus aureus | ||
| 9. | ALA530275 | TCMDC-125825 | MIC | > | 10 | uM | ALA4296188 | Median N= 2; Maxinhib 12.3 Pct | nM | Acinetobacter baumannii | ||
| 10. | ALA530275 | TCMDC-125825 | MIC | > | 10 | uM | ALA4296187 | Median N= 2; Maxinhib 21.8 Pct | nM | Pseudomonas aeruginosa | ||
| 11. | ALA530275 | TCMDC-125825 | MIC | > | 10 | uM | ALA4296186 | Median N= 2; Maxinhib 16.6 Pct | nM | Klebsiella pneumoniae | ||
| 12. | ALA530275 | TCMDC-125825 | MIC | > | 10 | uM | ALA4296185 | Median N= 2; Maxinhib 4.4 Pct | nM | Escherichia coli | ||
| 13. | ALA530275 | TCMDC-125825 | MIC | > | 10 | uM | ALA4296190 | Median N= 2; Maxinhib 30.9 Pct | nM | Cryptococcus neoformans | ||
| 14. | ALA530275 | TCMDC-125825 | MIC | > | 10 | uM | ALA4296189 | Median N= 2; Maxinhib 5.1 Pct | nM | Candida albicans | ||
| 15. | ALA530275 | TCMDC-125825 | Inhibition | 23.7 | % | ALA4513102 | Not Active | % | Naegleria gruberi | |||
| 16. | ALA530275 | TCMDC-125825 | Inhibition | 0 | ALA3987223 | Not Active | % | Homo sapiens | ||||
| 17. | ALA530275 | TCMDC-125825 | Inhibition | 0 | ALA3987222 | Not Active | % | Homo sapiens | ||||
| 18. | ALA530275 | TCMDC-125825 | Ratio IC50 | = | 30 | ALA4369193 | ||||||
| 19. | ALA530275 | TCMDC-125825 | IC50 | > | 25 | uM | ALA4369192 | nM | Homo sapiens | |||
| 20. | ALA530275 | TCMDC-125825 | IC50 | = | 0.83 | uM | ALA4369191 | 6.08 | nM | Trypanosoma brucei brucei |
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