# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA528437 | TCMDC-124162 | Ratio | = | 1.08 | ALA2448810 | Plasmodium falciparum | |||||
2. | ALA528437 | TCMDC-124162 | Toxicity | = | 4 | ALA2363025 | Dead | Schistosoma mansoni | ||||
3. | ALA528437 | TCMDC-124162 | Toxicity | = | 4 | ALA2363024 | Round, degenerate, slow | Schistosoma mansoni | ||||
4. | ALA528437 | TCMDC-124162 | Toxicity | = | 3 | ALA2363023 | Dark, round slow | Schistosoma mansoni | ||||
5. | ALA528437 | TCMDC-124162 | Inhibition | = | 97.6 | % | ALA2094262 | % | Mycobacterium tuberculosis | |||
6. | ALA528437 | TCMDC-124162 | Inhibition | = | 102 | % | ALA2094261 | % | Mycobacterium tuberculosis | |||
7. | ALA528437 | TCMDC-124162 | LD50 | = | 1.59 | uM | ALA2094265 | uM | Homo sapiens | |||
8. | ALA528437 | TCMDC-124162 | MIC90 | = | 3.33 | uM | ALA2094264 | nM | Mycobacterium tuberculosis | |||
9. | ALA528437 | TCMDC-124162 | MIC90 | = | 5.75 | uM | ALA2094263 | nM | Mycobacterium tuberculosis | |||
10. | ALA528437 | TCMDC-124162 | IC50 | = | 4 | uM | ALA2028075 | 5.40 | nM | Trypanosoma brucei rhodesiense | ||
11. | ALA528437 | TCMDC-124162 | IC50 | = | 3.783 | uM | ALA2028074 | 5.42 | nM | Trypanosoma brucei brucei | ||
12. | ALA528437 | TCMDC-124162 | IC50 | = | 3.749 | uM | ALA2028073 | 5.43 | nM | Trypanosoma cruzi | ||
13. | ALA528437 | TCMDC-124162 | EC50 | = | 313 | nM | ALA2028071 | 6.50 | nM | Plasmodium falciparum | ||
14. | ALA528437 | TCMDC-124162 | EC50 | = | 501 | nM | ALA2028072 | 6.30 | nM | Plasmodium falciparum | ||
15. | ALA528437 | TCMDC-124162 | Inhibition | = | 99 | % | ALA2028070 | % | Plasmodium falciparum | |||
16. | ALA528437 | TCMDC-124162 | IC50 | = | 9.306 | uM | ALA2028077 | 5.03 | nM | Homo sapiens | ||
17. | ALA528437 | TCMDC-124162 | IC50 | = | 4.057 | uM | ALA2028076 | 5.39 | nM | Leishmania infantum | ||
18. | ALA528437 | TCMDC-124162 | IC50 | = | 739.1 | nM | ALA3392923 | 6.13 | nM | Plasmodium falciparum | ||
19. | ALA528437 | TCMDC-124162 | IC50 | > | 1 | uM | ALA3301567 | nM | Plasmodium falciparum (isolate 3D7) | |||
20. | ALA528437 | TCMDC-124162 | IC50 | > | 1 | uM | ALA3301564 | nM | Plasmodium falciparum |