# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA533269 | TCMDC-123794 | IC50 | = | 152 | nM | ALA2114020 | 6.82 | nM | Plasmodium falciparum K1 | ||
2. | ALA533269 | TCMDC-123794 | IC50 | = | 0 | nM | ALA2114018 | nM | Plasmodium falciparum | |||
3. | ALA533269 | TCMDC-123794 | Reduced_parasitemia | 0 | ALA2114011 | Not Active | Plasmodium berghei | |||||
4. | ALA533269 | TCMDC-123794 | Relative metabolic rate | 0 | ALA2114009 | Moderate | ||||||
5. | ALA533269 | TCMDC-123794 | Half-life | = | 29 | min | ALA2114008 | hr | ||||
6. | ALA533269 | TCMDC-123794 | CLint | = | 60 | uL min-1 mg-1 | ALA2114007 | uL min-1 mg-1 | ||||
7. | ALA533269 | TCMDC-123794 | solubility | = | 12.5 | ug mL-1 | ALA2114006 | ug.mL-1 | ||||
8. | ALA533269 | TCMDC-123794 | solubility | = | 12.5 | ug mL-1 | ALA2114005 | ug.mL-1 | ||||
9. | ALA533269 | TCMDC-123794 | Inhibition | = | 20 | % | ALA2114004 | % | Homo sapiens | |||
10. | ALA533269 | TCMDC-123794 | IC50 | = | 245 | nM | ALA2114002 | 6.61 | nM | Plasmodium falciparum | ||
11. | ALA533269 | TCMDC-123794 | IC50 | = | 345 | nM | ALA2114000 | 6.46 | nM | Plasmodium falciparum | ||
12. | ALA533269 | TCMDC-123794 | Inhibition | = | -0.97 | % | ALA3436044 | % | Leishmania mexicana | |||
13. | ALA533269 | TCMDC-123794 | Inhibition | = | -1.81 | % | ALA3436043 | % | Plasmodium falciparum | |||
14. | ALA533269 | TCMDC-123794 | Inhibition | = | -2.25 | % | ALA3436042 | % | Homo sapiens | |||
15. | ALA533269 | TCMDC-123794 | Inhibition | = | 100 | % | ALA1054500 | % | Plasmodium falciparum | |||
16. | ALA533269 | TCMDC-123794 | Inhibition | = | 99 | % | ALA1054501 | % | Plasmodium falciparum | |||
17. | ALA533269 | TCMDC-123794 | Inhibition | = | 0 | % | ALA1054504 | % | Homo sapiens | |||
18. | ALA533269 | TCMDC-123794 | Inhibition | = | 0 | % | ALA1054502 | % | Plasmodium falciparum | |||
19. | ALA533269 | TCMDC-123794 | XC50 | = | 0.054 | uM | ALA1054503 | 7.27 | nM | Plasmodium falciparum | ||
20. | ALA533269 | TCMDC-123794 | IFI | = | 0 | % | ALA1054505 | % |