# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA531738 | 2; MMV665875 | Activity | 0 | ALA4668029 | Active | Trypanosoma cruzi | |||||
2. | ALA531738 | 2; MMV665875 | IC50 | = | 0.4 | uM | ALA4668028 | 6.40 | nM | Trypanosoma brucei rhodesiense | ||
3. | ALA531738 | 2; MMV665875 | IC50 | = | 11.5 | uM | ALA4668027 | 4.94 | nM | Trypanosoma brucei brucei | ||
4. | ALA531738 | 2; MMV665875 | IC50 | = | 16.9 | uM | ALA4668026 | 4.77 | nM | Trypanosoma cruzi | ||
5. | ALA531738 | 2; MMV665875 | INH | = | 11.7 | % | ALA4668021 | % | Rattus norvegicus | |||
6. | ALA531738 | 2; MMV665875 | INH | = | 9.9 | % | ALA4668020 | % | Rattus norvegicus | |||
7. | ALA531738 | 2; MMV665875 | INH | = | 8.4 | % | ALA4668015 | % | Homo sapiens | |||
8. | ALA531738 | 2; MMV665875 | INH | = | 4.7 | % | ALA4668014 | % | Homo sapiens | |||
9. | ALA531738 | 2; MMV665875 | Ki | = | 10 | uM | ALA4668012 | 5.00 | nM | Trypanosoma brucei rhodesiense | ||
10. | ALA531738 | 2; MMV665875 | INH | = | 62.1 | % | ALA4668005 | % | Trypanosoma cruzi | |||
11. | ALA531738 | 2; MMV665875 | INH | = | 87.8 | % | ALA4668004 | % | Trypanosoma cruzi | |||
12. | ALA531738 | 2; MMV665875 | INH | = | 64.5 | % | ALA4667994 | % | Trypanosoma cruzi | |||
13. | ALA531738 | 2; MMV665875 | INH | = | 74.8 | % | ALA4667993 | % | Trypanosoma cruzi | |||
14. | ALA531738 | 2; MMV665875 | INH | = | 56.4 | % | ALA4667992 | % | Trypanosoma cruzi | |||
15. | ALA531738 | 2; MMV665875 | IC50 | = | 38 | uM | ALA4667991 | 4.42 | nM | Trypanosoma brucei rhodesiense | ||
16. | ALA531738 | 2; MMV665875 | IC50 | = | 51 | uM | ALA4667989 | 4.29 | nM | Trypanosoma cruzi | ||
17. | ALA531738 | 2; MMV665875 | IC50 | = | 145 | uM | ALA4667988 | nM | Trypanosoma cruzi | |||
18. | ALA531738 | 2; MMV665875 | INH | = | 71 | % | ALA4667983 | % | Trypanosoma brucei rhodesiense | |||
19. | ALA531738 | 2; MMV665875 | INH | = | 67 | % | ALA4667982 | % | Trypanosoma brucei rhodesiense | |||
20. | ALA531738 | 2; MMV665875 | INH | = | 80 | % | ALA4667981 | % | Trypanosoma cruzi |