# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA581422 | TCMDC-123940 | Inhibition | = | -0.74 | % | ALA3436044 | % | Leishmania mexicana | |||
2. | ALA581422 | TCMDC-123940 | Inhibition | = | 0.24 | % | ALA3436043 | % | Plasmodium falciparum | |||
3. | ALA581422 | TCMDC-123940 | Inhibition | = | 0.97 | % | ALA3436042 | % | Homo sapiens | |||
4. | ALA581422 | TCMDC-123940 | LC50 | = | 42 | uM | ALA4007891 | nM | Mus musculus | |||
5. | ALA581422 | TCMDC-123940 | IC50 | = | 2.3 | uM | ALA4007890 | 5.64 | nM | Homo sapiens | ||
6. | ALA581422 | TCMDC-123940 | Ratio IC50 | = | 39 | ALA4007867 | ||||||
7. | ALA581422 | TCMDC-123940 | IC50 | = | 63 | uM | ALA4007866 | 4.20 | nM | Homo sapiens | ||
8. | ALA581422 | TCMDC-123940 | IC50 | = | 1.6 | uM | ALA4007862 | 5.80 | nM | Homo sapiens | ||
9. | ALA581422 | TCMDC-123940 | IC50 | = | 195 | nM | ALA1047861 | 6.71 | nM | Plasmodium falciparum | ||
10. | ALA581422 | TCMDC-123940 | Ratio IC50 | = | 1.9 | ALA1047860 | Plasmodium falciparum | |||||
11. | ALA581422 | TCMDC-123940 | t1/2 | = | 16 | min | ALA1050502 | hr | ||||
12. | ALA581422 | TCMDC-123940 | Activity | = | 40.5 | % | ALA1050500 | % | Plasmodium berghei | |||
13. | ALA581422 | TCMDC-123940 | Activity | = | 32.4 | % | ALA1050499 | % | Plasmodium berghei | |||
14. | ALA581422 | TCMDC-123940 | Ratio IC50 | = | 1.2 | ALA1047868 | Plasmodium falciparum | |||||
15. | ALA581422 | TCMDC-123940 | Ratio CC50/IC50 | = | 4525 | ALA1047867 | ||||||
16. | ALA581422 | TCMDC-123940 | CC50 | = | 457 | uM | ALA1047866 | nM | Homo sapiens | |||
17. | ALA581422 | TCMDC-123940 | IC50 | = | 124 | nM | ALA1047865 | 6.91 | nM | Plasmodium falciparum | ||
18. | ALA581422 | TCMDC-123940 | IC50 | = | 101 | nM | ALA1047864 | 7.00 | nM | Plasmodium falciparum | ||
19. | ALA581422 | TCMDC-123940 | Ratio CC50/IC50 | > | 202 | ALA1047863 | ||||||
20. | ALA581422 | TCMDC-123940 | CC50 | > | 39.5 | uM | ALA1047862 | nM | Homo sapiens |