Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	ALA535650	Mefloquine	INH	=	54	%	ALA3631596			%	Homo sapiens
2.	ALA535650	Mefloquine	INH	=	54	%	ALA3631594			%	Homo sapiens
3.	ALA535650	Mefloquine	IC50	=	5	nM	ALA3405930	8.30		nM	Plasmodium falciparum
4.	ALA535650	Mefloquine	IC50	=	6	nM	ALA3405931	8.22		nM	Plasmodium falciparum
5.	ALA535650	Mefloquine	IC50	=	5	nM	ALA3405932	8.30		nM	Plasmodium falciparum
6.	ALA535650	Mefloquine	Potency		17.783	uM	ALA3562077		inconclusive	nM
7.	ALA535650	Mefloquine	Selectivity index	=	2		ALA4303808
8.	ALA535650	Mefloquine	CC50	=	33.02	uM	ALA4303807		33.02 ± 7.96	nM	Homo sapiens
9.	ALA535650	Mefloquine	IC50	=	14.15	uM	ALA4303806	4.85	14.15 ± 10.05	nM	Severe acute respiratory syndrome coronavirus 2
10.	ALA535650	Mefloquine	Inhibition	=	93.28	%	ALA4303805			%	Severe acute respiratory syndrome coronavirus 2
11.	ALA535650	Mefloquine	Inhibition index	=	-0.126		ALA4303819				Severe acute respiratory syndrome coronavirus 2
12.	ALA535650	Mefloquine	Selectivity index	=	2.3		ALA4303828
13.	ALA535650	Mefloquine	Selectivity index	=	2.61		ALA4303825
14.	ALA535650	Mefloquine	Activity		0		ALA4303830				Severe acute respiratory syndrome coronavirus 2
15.	ALA535650	Mefloquine	CC50	=	18.53	uM	ALA4303827			nM	Chlorocebus sabaeus
16.	ALA535650	Mefloquine	IC50	=	8.06	uM	ALA4303826	5.09		nM	Severe acute respiratory syndrome coronavirus 2
17.	ALA535650	Mefloquine	CC50	=	18.53	uM	ALA4303824			nM	Chlorocebus sabaeus
18.	ALA535650	Mefloquine	IC50	=	7.11	uM	ALA4303823	5.15		nM	Severe acute respiratory syndrome coronavirus 2
19.	ALA535650	Mefloquine	AC50	=	7.13	uM	ALA3214853	5.15	active	nM
20.	ALA535650	Mefloquine	Potency		14.125	uM	ALA3215270		inconclusive	nM