| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA557593 | 3kg (T-2585.HCl) | Ratio | = | 0.05 | ALA848576 | Homo sapiens | |||||
| 2. | ALA557593 | 3kg (T-2585.HCl) | Selectivity | = | 14000 | ALA851109 | Homo sapiens | |||||
| 3. | ALA557593 | 3kg (T-2585.HCl) | Emesis | = | 4 | vomiting/tested | ALA671866 | vomiting/tested | Canis lupus familiaris | |||
| 4. | ALA557593 | 3kg (T-2585.HCl) | Emesis | = | 8 | vomiting/tested | ALA671865 | vomiting/tested | Canis lupus familiaris | |||
| 5. | ALA557593 | 3kg (T-2585.HCl) | Emesis | = | 4 | vomiting/tested | ALA819643 | vomiting/tested | Homo sapiens | |||
| 6. | ALA557593 | 3kg (T-2585.HCl) | Emesis | = | 4 | vomiting/tested | ALA819641 | vomiting/tested | Homo sapiens | |||
| 7. | ALA557593 | 3kg (T-2585.HCl) | Ki | = | 2.6 | nM | ALA763942 | 8.59 | nM | Homo sapiens | ||
| 8. | ALA557593 | 3kg (T-2585.HCl) | ED50 | = | 0.033 | mg kg-1 | ALA683972 | mg.kg-1 | Cavia porcellus | |||
| 9. | ALA557593 | 3kg (T-2585.HCl) | Heart rate | = | 3 | delta beats min-1 | ALA683506 | delta beats min-1 | Cavia porcellus | |||
| 10. | ALA557593 | 3kg (T-2585.HCl) | Heart rate | = | 5 | delta beats min-1 | ALA685932 | delta beats min-1 | Cavia porcellus | |||
| 11. | ALA557593 | 3kg (T-2585.HCl) | Heart rate | = | 4 | delta beats min-1 | ALA685931 | delta beats min-1 | Cavia porcellus | |||
| 12. | ALA557593 | 3kg (T-2585.HCl) | ED50 | = | 0.063 | mg kg-1 | ALA683970 | mg.kg-1 | Cavia porcellus | |||
| 13. | ALA557593 | 3kg (T-2585.HCl) | Reduction | = | 84 | % | ALA688875 | % | Cavia porcellus | |||
| 14. | ALA557593 | 3kg (T-2585.HCl) | Reduction | = | 57 | % | ALA688874 | % | Cavia porcellus | |||
| 15. | ALA557593 | 3kg (T-2585.HCl) | Reduction | = | 37 | % | ALA688873 | % | Cavia porcellus | |||
| 16. | ALA557593 | 3kg (T-2585.HCl) | IC50 | = | 200 | nM | ALA763668 | 6.70 | nM | Homo sapiens | ||
| 17. | ALA557593 | 3kg (T-2585.HCl) | IC50 | = | 0.13 | nM | ALA767082 | 9.89 | nM | Homo sapiens | ||
| 18. | ALA557593 | 3kg (T-2585.HCl) | IC50 | = | 1800 | nM | ALA761549 | 5.75 | nM | Homo sapiens | ||
| 19. | ALA557593 | 3kg (T-2585.HCl) | IC50 | = | 1300 | nM | ALA762548 | 5.89 | nM | Homo sapiens | ||
| 20. | ALA557593 | 3kg (T-2585.HCl) | IC50 | = | 10000 | nM | ALA760754 | 5.00 | nM | Homo sapiens |
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