# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA557193 | 38a | Activity | = | 20 | mmHg | ALA895244 | mmHg | Callithrix jacchus | |||
2. | ALA557193 | 38a | IC50 | = | 3 | nM | ALA895254 | 8.52 | nM | Callithrix jacchus | ||
3. | ALA557193 | 38a | IC50 | = | 1 | nM | ALA895253 | 9.00 | nM | Homo sapiens | ||
4. | ALA557193 | 38a | IC50 | = | 1 | nM | ALA895252 | 9.00 | nM | Homo sapiens | ||
5. | ALA557193 | 38a | Activity | 0 | ALA895247 | Dose-dependent effect | Callithrix jacchus | |||||
6. | ALA557193 | 38a | CL | = | 5.2 | ml/min.kg | ALA895242 | mL.min-1.kg-1 | Callithrix jacchus | |||
7. | ALA557193 | 38a | Vdss | = | 0.6 | L/Kg | ALA895241 | L.kg-1 | Callithrix jacchus | |||
8. | ALA557193 | 38a | t1/2 | = | 2 | hr | ALA895240 | hr | Callithrix jacchus | |||
9. | ALA557193 | 38a | F | = | 16 | % | ALA895239 | % | Callithrix jacchus | |||
10. | ALA557193 | 38a | F | = | 16 | % | ALA895238 | % | Callithrix jacchus | |||
11. | ALA557193 | 38a | Activity | 0 | ALA895249 | Active | Callithrix jacchus | |||||
12. | ALA557193 | 38a | Activity | 0 | ALA895248 | Active | Callithrix jacchus | |||||
13. | ALA557193 | 38a | Activity | 0 | ALA895251 | Not Active | Bos taurus | |||||
14. | ALA557193 | 38a | Activity | 0 | ALA895250 | Not Active | ||||||
15. | ALA557193 | 38a | Activity | = | -9 | mmHg | ALA895243 | mmHg | Callithrix jacchus | |||
16. | ALA557193 | 38a | pKa | = | 9.13 | ALA895237 | ||||||
17. | ALA557193 | 38a | Solubility | = | 56 | g/L | ALA895236 | ug.mL-1 | ||||
18. | ALA557193 | 38a | Solubility | = | 11 | g/L | ALA895235 | ug.mL-1 | ||||
19. | ALA557193 | 38a | LogP | = | 1.96 | ALA895234 | ||||||
20. | ALA557193 | 38a | IC50 | = | 3 | nM | ALA895233 | 8.52 | nM | Callithrix jacchus |