| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA560895 | 9, SNX-2112 | IC50 relative | < | 100 | nM | ALA5303715 | Active | nM | Homo sapiens | ||
| 2. | ALA560895 | 9, SNX-2112 | Activity | 0 | ALA3378861 | Not Active | Homo sapiens | |||||
| 3. | ALA560895 | 9, SNX-2112 | inhibition | = | 1.58 | % | ALA4513082 | % | Severe acute respiratory syndrome coronavirus 2 | |||
| 4. | ALA560895 | 9, SNX-2112 | inhibition | = | 7.29 | % | ALA4513082 | % | Severe acute respiratory syndrome coronavirus 2 | |||
| 5. | ALA560895 | 9, SNX-2112 | Inhibition | = | -14.086 | % | ALA4495582 | % | Severe acute respiratory syndrome coronavirus 2 | |||
| 6. | ALA560895 | 9, SNX-2112 | Inhibition | = | -5.39 | % | ALA4495582 | % | Severe acute respiratory syndrome coronavirus 2 | |||
| 7. | ALA560895 | 9, SNX-2112 | IC50 | = | 3 | nM | ALA2212191 | 8.52 | nM | Homo sapiens | ||
| 8. | ALA560895 | 9, SNX-2112 | EC50 | = | 19 | nM | ALA2212645 | 7.72 | nM | Homo sapiens | ||
| 9. | ALA560895 | 9, SNX-2112 | Papp | = | 1.1 | ucm/s | ALA2212646 | ucm/s | Homo sapiens | |||
| 10. | ALA560895 | 9, SNX-2112 | Ratio | = | 35 | ALA2212190 | Homo sapiens | |||||
| 11. | ALA560895 | 9, SNX-2112 | Fu | = | 6 | % | ALA2212189 | Mus musculus | ||||
| 12. | ALA560895 | 9, SNX-2112 | Fu | = | 9.6 | % | ALA2212188 | Rattus norvegicus | ||||
| 13. | ALA560895 | 9, SNX-2112 | Fu | = | 6.8 | % | ALA2212187 | Homo sapiens | ||||
| 14. | ALA560895 | 9, SNX-2112 | CLH | = | 301 | ml/min.kg | ALA2212186 | mL.min-1.kg-1 | Mus musculus | |||
| 15. | ALA560895 | 9, SNX-2112 | CLH | = | 54 | ml/min.kg | ALA2212185 | mL.min-1.kg-1 | Rattus norvegicus | |||
| 16. | ALA560895 | 9, SNX-2112 | CLH | = | 54 | ml/min.kg | ALA2212184 | mL.min-1.kg-1 | Homo sapiens | |||
| 17. | ALA560895 | 9, SNX-2112 | Cmax | = | 1724 | ng/ml | ALA2212647 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Mus musculus | ||
| 18. | ALA560895 | 9, SNX-2112 | Tmax | = | 1 | hr | ALA2212181 | hr | Mus musculus | |||
| 19. | ALA560895 | 9, SNX-2112 | AUC | = | 8517 | ng.hr/ml | ALA2212178 | ng.hr.mL-1 | Mus musculus | |||
| 20. | ALA560895 | 9, SNX-2112 | AUC/dose | = | 341 | ng.hr/ml/mg/kg | ALA2212175 | ng.hr/ml/mg/kg | Mus musculus |
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