# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA561798 | 1b | logD | = | 1.4 | ALA5243725 | ||||||
2. | ALA561798 | 1b | IC50 | = | 2 | uM | ALA5243724 | 5.70 | nM | |||
3. | ALA561798 | 1b | IC50 | = | 1.2 | uM | ALA5243723 | 5.92 | nM | |||
4. | ALA561798 | 1b | INH | = | 41 | % | ALA1056534 | % | Mus musculus | |||
5. | ALA561798 | 1b | FC | = | 2 | ALA1056533 | Homo sapiens | |||||
6. | ALA561798 | 1b | PPB | = | 64.8 | % | ALA1056532 | % | Rattus norvegicus | |||
7. | ALA561798 | 1b | AUC | = | 10.75 | microg.hr/mL | ALA1056538 | ng.hr.mL-1 | Rattus norvegicus | |||
8. | ALA561798 | 1b | t1/2 | = | 2.59 | hr | ALA1056537 | hr | Rattus norvegicus | |||
9. | ALA561798 | 1b | Tmax | = | 0.5 | hr | ALA1056536 | hr | Rattus norvegicus | |||
10. | ALA561798 | 1b | Cmax | = | 2.9 | ug ml-1 | ALA1056535 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
11. | ALA561798 | 1b | IC50 | = | 2 | uM | ALA1054938 | 5.70 | nM | Homo sapiens | ||
12. | ALA561798 | 1b | IC50 | = | 1.2 | uM | ALA1054937 | 5.92 | nM | Oryctolagus cuniculus | ||
13. | ALA561798 | 1b | IC50 | = | 1.4 | uM | ALA1054936 | 5.85 | nM | |||
14. | ALA561798 | 1b | Ratio IC50 | = | 2 | ALA1056531 | Oryctolagus cuniculus |