| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA539697 | Dabigatran etexilate | F | = | 6 | % | ALA4426729 | % | ||||
| 2. | ALA539697 | Dabigatran etexilate | inhibition | = | -3.27 | % | ALA4808150 | % | Homo sapiens | |||
| 3. | ALA539697 | Dabigatran etexilate | inhibition | = | 26.29 | % | ALA4808149 | % | Homo sapiens | |||
| 4. | ALA539697 | Dabigatran etexilate | Hit score | = | 0.242 | ALA4303810 | Severe acute respiratory syndrome coronavirus 2 | |||||
| 5. | ALA539697 | Dabigatran etexilate | Inhibition | = | 4.4 | % | ALA4303805 | % | Severe acute respiratory syndrome coronavirus 2 | |||
| 6. | ALA539697 | Dabigatran etexilate | Ratio | = | 13.8 | ALA4229789 | ||||||
| 7. | ALA539697 | Dabigatran etexilate | Papp | = | 29 | ucm/s | ALA4229788 | ucm/s | ||||
| 8. | ALA539697 | Dabigatran etexilate | F | = | 6.7 | % | ALA4229787 | % | Homo sapiens | |||
| 9. | ALA539697 | Dabigatran etexilate | IC50 | = | 3.26 | 10'-4microM | ALA4148489 | 9.49 | nM | |||
| 10. | ALA539697 | Dabigatran etexilate | NOAEL | 0 | ALA4672683 | Not Determined | Homo sapiens | |||||
| 11. | ALA539697 | Dabigatran etexilate | F | = | 1.9 | % | ALA4672682 | % | ||||
| 12. | ALA539697 | Dabigatran etexilate | t1/2 | = | 1.2 | hr | ALA4672681 | hr | ||||
| 13. | ALA539697 | Dabigatran etexilate | Vdss | = | 0.54 | L/Kg | ALA4672680 | L.kg-1 | ||||
| 14. | ALA539697 | Dabigatran etexilate | Ratio | 0 | ALA4672679 | Not Determined | ||||||
| 15. | ALA539697 | Dabigatran etexilate | CL | = | 0.59 | L/hr/kg | ALA4672678 | mL.min-1.kg-1 | ||||
| 16. | ALA539697 | Dabigatran etexilate | AUC/dose | = | 3 | kg.hr/L | ALA4672677 | kg.hr/L | ||||
| 17. | ALA539697 | Dabigatran etexilate | MRT | = | 1.6 | hr | ALA4672676 | hr | ||||
| 18. | ALA539697 | Dabigatran etexilate | pIC50 | < | 4.7 | ALA4651403 | No. Measurements = 1 | nM | Severe acute respiratory syndrome coronavirus 2 | |||
| 19. | ALA539697 | Dabigatran etexilate | IC50 | > | 0 | M | ALA4651403 | No. Measurements = 1 | nM | Severe acute respiratory syndrome coronavirus 2 | ||
| 20. | ALA539697 | Dabigatran etexilate | inhibition | = | -0.05 | % | ALA4513082 | % | Severe acute respiratory syndrome coronavirus 2 |
The page will load shortly, Thanks for your patience!